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Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn’s disease

dc.contributor.authorDiederen, Kay
dc.contributor.authorLi, Jia V.
dc.contributor.authorDonachie, Gillian E.
dc.contributor.authorde Meij, Tim G.
dc.contributor.authorde Waart, Dirk R.
dc.contributor.authorHakvoort, Theodorus B. M.
dc.contributor.authorKindermann, Angelika
dc.contributor.authorWagner, Josef
dc.contributor.authorAuyeung, Victoria
dc.contributor.authorte Velde, Anje A.
dc.contributor.authorHeinsbroek, Sigrid E. M.
dc.contributor.authorBenninga, Marc A.
dc.contributor.authorKinross, James
dc.contributor.authorWalker, Alan W.
dc.contributor.authorde Jonge, Wouter J.
dc.contributor.authorSeppen, Jurgen
dc.date.accessioned2020-11-04T10:18:01Z
dc.date.available2020-11-04T10:18:01Z
dc.date.issued2020-11-03
dc.identifier.citationDiederen , K , Li , J V , Donachie , G E , de Meij , T G , de Waart , D R , Hakvoort , T B M , Kindermann , A , Wagner , J , Auyeung , V , te Velde , A A , Heinsbroek , S E M , Benninga , M A , Kinross , J , Walker , A W , de Jonge , W J & Seppen , J 2020 , ' Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn’s disease ' , Scientific Reports , vol. 10 , 18879 , pp. 18879 . https://doi.org/10.1038/s41598-020-75306-zen
dc.identifier.issn2045-2322
dc.identifier.otherPURE: 179049681
dc.identifier.otherPURE UUID: 7dc4feda-d2bd-4564-9a3d-a03d6d164519
dc.identifier.otherRIS: urn:35F6CAEF883122B1B516F126FD9B8B01
dc.identifier.otherRIS: Diederen2020
dc.identifier.otherORCID: /0000-0001-5099-8495/work/82960046
dc.identifier.otherPubMed: 33144591
dc.identifier.otherScopus: 85094873366
dc.identifier.otherWOS: 000587347400001
dc.identifier.urihttps://hdl.handle.net/2164/15318
dc.descriptionGD and AWW receive core funding support from the Scottish Government’s Rural and Environmental Science and Analytical Services (RESAS) Division. JW was funded by the Wellcome Trust [Grant No. 098051]. JVL is funded by MRC New Investigator Grant (MR/P002536/1) and ERC Starting Grant (715662). JK is funded by NIHR: II-OL-1116-10027, NIH: R01-CA204403-01A1, Horizon H2020: ITN GROWTH. Imperial Biomedical Research Centre, SAGES research grant. Infrastructure support for this research was provided by the NIHR Imperial biomedical Research Centre (BRC). Microbiota analyses were carried out using the Maxwell computer cluster at the University of Aberdeen. We thank the Illumina MiSeq team at the Wellcome Sanger Institute for their assistance. This work was partially described in the Ph.D. thesis of KD (Retrieved 2020, Pediatric inflammatory bowel disease Monitoring, nutrition and surgery, https://pure.uva.nl/ws/files/23176012/Thesis_complete_.pdf).en
dc.format.extent17
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.rightsThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectgastronenterologyen
dc.subjectgastrointestinal diseasesen
dc.subjectmicrobiologyen
dc.subjectDEXTRAN SULFATE SODIUMen
dc.subjectINTESTINAL MICROBIOTAen
dc.subjectNMR-SPECTROSCOPYen
dc.subjectRECEPTORen
dc.subjectTGR5en
dc.subjectL-CARNITINEen
dc.subjectINFLAMMATORY-BOWEL-DISEASEen
dc.subjectCOLITISen
dc.subjectCORTICOSTEROIDSen
dc.subjectQR Microbiologyen
dc.subjectR Medicineen
dc.subjectGeneralen
dc.subjectMedical Research Council (MRC)en
dc.subjectSupplementary Dataen
dc.subjectLegends for supplementary Figures 1–3.en
dc.subjectSupplementary Figure 1en
dc.subjectSupplementary Figure 2.en
dc.subjectSupplementary Figure 3.en
dc.subjectSupplementary Table 2.en
dc.subjectSupplementary Table 3.en
dc.subject.lccQRen
dc.subject.lccRen
dc.titleExclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn’s diseaseen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Mandarinen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1038/s41598-020-75306-z
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85094873366&partnerID=8YFLogxKen
dc.identifier.vol10en


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