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dc.contributor.authorBuschhaus, Magdalena J
dc.contributor.authorBecker, Stefan
dc.contributor.authorPorter, Andrew J
dc.contributor.authorBarelle, Caroline J
dc.date.accessioned2021-03-02T00:20:34Z
dc.date.available2021-03-02T00:20:34Z
dc.date.issued2020-09
dc.identifier.citationBuschhaus , M J , Becker , S , Porter , A J & Barelle , C J 2020 , ' Isolation of highly selective IgNAR variable single-domains against a human therapeutic Fc scaffold and their application as tailor-made bioprocessing reagents ' , Protein engineering, design & selection : PEDS , vol. 32 , no. 9 , pp. 385-399 . https://doi.org/10.1093/protein/gzaa002en
dc.identifier.issn1741-0126
dc.identifier.otherPURE: 158360204
dc.identifier.otherPURE UUID: 8db74b7b-d163-4dea-9166-794c848f48a9
dc.identifier.otherPubMed: 32119084
dc.identifier.otherWOS: 000536506800001
dc.identifier.otherScopus: 85082561719
dc.identifier.urihttps://hdl.handle.net/2164/15951
dc.descriptionFunding This work was supported by the Industrial Biotechnology Innovation Centre, and Merck KGaA. Acknowledgements The authors would like to thank Iris Willenbücher and Kerstin Hallstein for the BIAcore™ analysis and Nadine Barron for the bio-layer interferometry work.en
dc.format.extent15
dc.language.isoeng
dc.relation.ispartofProtein engineering, design & selection : PEDSen
dc.rightsThis is a pre-copyedited, author-produced version of an article accepted for publication in Protein Engineering, Design and Selection following peer review. The version of record Buschhaus, MJ, Becker, S, Porter, AJ & Barelle, CJ 2020, 'Isolation of highly selective IgNAR variable single-domains against a human therapeutic Fc scaffold and their application as tailor-made bioprocessing reagents', Protein engineering, design & selection : PEDS, vol. 32, no. 9, pp. 385-39, is available online at: https://doi.org/10.1093/protein/gzaa002.en
dc.subjectaffinity liganden
dc.subjectphage displayen
dc.subjectSEED bispecific antibody platformen
dc.subjectshark IgNARen
dc.subjectvariable new antigen receptoren
dc.subjectBISPECIFIC ANTIBODIESen
dc.subjectCOMPLEXen
dc.subjectIMMUNOGLOBULINen
dc.subjectANTIBODY FRAGMENTSen
dc.subjectANTIGEN RECEPTOR IGNARen
dc.subjectPLATFORMen
dc.subjectAFFINITY LIGANDSen
dc.subjectSHARKen
dc.subjectSEEDen
dc.subjectPURIFICATIONen
dc.subjectR Medicineen
dc.subjectBioengineeringen
dc.subjectMolecular Biologyen
dc.subjectBiochemistryen
dc.subjectBiotechnologyen
dc.subject.lccRen
dc.titleIsolation of highly selective IgNAR variable single-domains against a human therapeutic Fc scaffold and their application as tailor-made bioprocessing reagentsen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Clinical Medicineen
dc.description.statusPeer revieweden
dc.description.versionPostprinten
dc.identifier.doihttps://doi.org/10.1093/protein/gzaa002
dc.date.embargoedUntil2021-03-02
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85082561719&partnerID=8YFLogxKen


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