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Dynamics of the transcriptional landscape during human fetal testis and ovary development

dc.contributor.authorLecluze, Estelle
dc.contributor.authorRolland, Antoine D.
dc.contributor.authorFilis, Panagiotis
dc.contributor.authorEvrard, Bertrand
dc.contributor.authorLeverrier-Penna, Sabrina
dc.contributor.authorBen Maamar, Millissia
dc.contributor.authorCoiffec, Isabelle
dc.contributor.authorLavoué, Vincent
dc.contributor.authorFowler , Paul A.
dc.contributor.authorMazaud Guittot, Séverine
dc.contributor.authorJégou, Bernard
dc.contributor.authorChalmel, Frédéric
dc.date.accessioned2021-05-14T23:07:17Z
dc.date.available2021-05-14T23:07:17Z
dc.date.issued2020-05
dc.identifier.citationLecluze , E , Rolland , A D , Filis , P , Evrard , B , Leverrier-Penna , S , Ben Maamar , M , Coiffec , I , Lavoué , V , Fowler , P A , Mazaud Guittot , S , Jégou , B & Chalmel , F 2020 , ' Dynamics of the transcriptional landscape during human fetal testis and ovary development ' , Human Reproduction , vol. 35 , no. 5 , pp. 1099-1119 . https://doi.org/10.1093/humrep/deaa041en
dc.identifier.issn0268-1161
dc.identifier.otherPURE: 157419703
dc.identifier.otherPURE UUID: e2d9eae8-f344-421d-98e8-fabb76c5f8f5
dc.identifier.otherPubMed: 32412604
dc.identifier.otherScopus: 85085905497
dc.identifier.otherORCID: /0000-0002-4831-9075/work/79059748
dc.identifier.otherWOS: 000569067100011
dc.identifier.urihttps://hdl.handle.net/2164/16470
dc.descriptionAcknowledgements We thank all members of the SEQanswers forums for helpful advice; Steven Salzberg and Cole Trapnell for continuous support with the ‘Tuxedo’ suite; and the UCSC Genome team members. Sequencing was performed by the GenomEast platform, a member of the ‘France Génomique’ consortium (ANR-10-INBS-0009). We thank Ms Linda Robertson, Ms Margaret Fraser, Ms Samantha Flannigan (University of Aberdeen) and the staff at Grampian NHS Pregnancy Counselling Service and all the staff of the Department of Obstetrics and Gynecology of the Rennes Sud Hospital for their expert assistance and help, and the participating women, without whom this study would not have been possible. The authors are grateful for Ms Gersende Lacombe and Mr Laurent Deleurme from the Biosit CytomeTri cytometry core facility of Rennes 1 University. Funding French National Institute of Health and Medical Research (Inserm); University of Rennes 1; French School of Public Health (EHESP); Swiss National Science Foundation [SNF n° CRS115_171007 to B.J.]; the French National Research Agency [ANR n° 16-CE14-0017-02 and n°18-CE14-0038-02 to F.C]; Medical Research Council [MR/L010011/1 to PAF]; European Community’s Seventh Framework Programme (FP7/2007–2013) [under grant agreement no 212885 to PAF]; European Union’s Horizon 2020 Research and Innovation Programme [under grant agreement no 825100 to P.A.F. and S.M.G.].en
dc.format.extent21
dc.language.isoeng
dc.relation.ispartofHuman Reproductionen
dc.rightsThis is a pre-copyedited, author-produced version of an article accepted for publication in Human Reproduction following peer review. The version of record Estelle Lecluze, Antoine D Rolland, Panagiotis Filis, Bertrand Evrard, Sabrina Leverrier-Penna, Millissia Ben Maamar, Isabelle Coiffec, Vincent Lavoué, Paul A Fowler, Séverine Mazaud-Guittot, Bernard Jégou, Frédéric Chalmel, Dynamics of the transcriptional landscape during human fetal testis and ovary development, Human Reproduction, Volume 35, Issue 5, May 2020, Pages 1099–1119 is available online at: https://doi.org/10.1093/humrep/deaa041.en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjecthuman gonad developmenten
dc.subjectfetal testisen
dc.subjectfetal ovaryen
dc.subjectsex differentiationen
dc.subjectdisorders of sex developmenten
dc.subjecttranscriptional profilingen
dc.subjectnovel unannotated transcriptsen
dc.subjectlong non-coding RNAsen
dc.subjectbulk RNA-sequencingen
dc.subjectproteomics informed by transcriptomicsen
dc.subjectR Medicineen
dc.subjectObstetrics and Gynaecologyen
dc.subjectReproductive Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/L010011/1en
dc.subjectEuropean Commissionen
dc.subject212885en
dc.subject825100en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleDynamics of the transcriptional landscape during human fetal testis and ovary developmenten
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Clinical Medicineen
dc.description.statusPeer revieweden
dc.description.versionPostprinten
dc.identifier.doihttps://doi.org/10.1093/humrep/deaa041
dc.date.embargoedUntil2021-05-15
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85085905497&partnerID=8YFLogxKen
dc.identifier.vol35en
dc.identifier.iss5en


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