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Prevention of Adverse Drug Reactions in Hospitalized Older Patients with Multi-morbidity and Polypharmacy : the SENATOR randomized controlled clinical trial

dc.contributor.authorO’Mahony, Denis
dc.contributor.authorGudmundsson, Adalsteinn
dc.contributor.authorSoiza, Roy L.
dc.contributor.authorPetrovic, Mirko
dc.contributor.authorJose Cruz-Jentoft, Alfonso
dc.contributor.authorCherubini, Antonio
dc.contributor.authorFordham, Richard
dc.contributor.authorByrne, Stephen
dc.contributor.authorDahly, Darren
dc.contributor.authorGallagher, Paul
dc.contributor.authorLavan, Amanda
dc.contributor.authorCurtin, Denis
dc.contributor.authorDalton, Kieran
dc.contributor.authorCullinane, Shane
dc.contributor.authorFlanagan, Evelyn
dc.contributor.authorShiely, Frances
dc.contributor.authorSamuelsson, Ólafur
dc.contributor.authorSverrisdóttir, Ástrós
dc.contributor.authorSubbarayan, Selvarani
dc.contributor.authorVandaele, Lore
dc.contributor.authorMeireson, Eline
dc.contributor.authorMontero-Errasquín, Beatriz
dc.contributor.authorRexach-Cano, Aurora
dc.contributor.authorCorrea-Pérez, Andrea
dc.contributor.authorLozano-Montoya, Isabel
dc.contributor.authorVélez-Díaz-Pallarés, Manuel
dc.contributor.authorCerenzia, Annarita
dc.contributor.authorCorradi, Samanta
dc.contributor.authorSoledad Cotorruelo Ferreiro, Maria
dc.contributor.authorDimitri, Federica
dc.contributor.authorMarinelli, Paolo
dc.contributor.authorMartelli, Gaia
dc.contributor.authorFong Soe Khioe, Rebekah
dc.contributor.authorEustace, Joseph
dc.date.accessioned2021-06-01T23:07:40Z
dc.date.available2021-06-01T23:07:40Z
dc.date.issued2020-07
dc.identifier.citationO’Mahony , D , Gudmundsson , A , Soiza , R L , Petrovic , M , Jose Cruz-Jentoft , A , Cherubini , A , Fordham , R , Byrne , S , Dahly , D , Gallagher , P , Lavan , A , Curtin , D , Dalton , K , Cullinane , S , Flanagan , E , Shiely , F , Samuelsson , Ó , Sverrisdóttir , Á , Subbarayan , S , Vandaele , L , Meireson , E , Montero-Errasquín , B , Rexach-Cano , A , Correa-Pérez , A , Lozano-Montoya , I , Vélez-Díaz-Pallarés , M , Cerenzia , A , Corradi , S , Soledad Cotorruelo Ferreiro , M , Dimitri , F , Marinelli , P , Martelli , G , Fong Soe Khioe , R & Eustace , J 2020 , ' Prevention of Adverse Drug Reactions in Hospitalized Older Patients with Multi-morbidity and Polypharmacy : the SENATOR randomized controlled clinical trial ' , Age and Ageing , vol. 49 , no. 4 , pp. 605-614 . https://doi.org/10.1093/ageing/afaa072en
dc.identifier.issn0002-0729
dc.identifier.otherPURE: 159747223
dc.identifier.otherPURE UUID: aa97b52d-32d5-477f-9edc-f56ff284af37
dc.identifier.otherORCID: /0000-0002-1397-4272/work/76608946
dc.identifier.otherScopus: 85087530568
dc.identifier.otherWOS: 000569008300020
dc.identifier.urihttps://hdl.handle.net/2164/16596
dc.descriptionAcknowledgements: The trial was co-ordinated and the trial database was managed by the staff of the Health Research Board Clinical Research Facilities at University College Cork (HRB CRF-C). The authors wish to thank the patients and staff of the participating hospitals for their cooperation: (i) Cork University Hospital, Cork, Ireland. (ii) Ghent University Hospital, Ghent, Belgium. (iii) Hospital Universitario Ramón y Cajal, Madrid, Spain. (iv) Ospedali Riuniti, Ancona, Italy. (v) Landspitali University Hospital, Reykjavik, Iceland. (vi) Aberdeen Royal Infirmary, Aberdeen, Scotland. The authors wish to acknowledge the contributions of the staff of the following organizations in the SENATOR trial: (i) ClinInfo S.A, Lyons, France (Philippe Foerster). (ii) ARTTIC International Management Services, Munich, Germany (Dr Otilia Postea). (iii) Clanwilliam Health, Dublin, Ireland (Joseph McMullin, Anthony Maguire). (iv) HRB Clinical Research Facility— Cork, Cork, Ireland (Mary-Claire O’Regan, Aoife Harvey, Ruben Keane, Máire McCarthy, Sarah O’Meara). The authors further wish to acknowledge the oversight of the external Scientific Advisory Board (SAB) and the Ethics and Safety Review Group (ESRG) during the conduct of the SENATOR trial. SAB members included: Prof. Cillian Twomey (chairperson), Prof. Peter Crome, Dr Paul Jansen, Prof. Anne Spinewine, Prof. Jamie Coleman, Prof. Tischa van der Cammen and Prof. Jose M. Ribera-Casado. ESRG members included Prof. Shaun O’Keeffe (chairperson), Prof. Liam Plant and Robin Webster (older person advocate). Funding: This work was supported by the European Commission’s Seventh Framework Programme (FP7/2007– 2013) (grant number 305930) as part of the SENATOR project.en
dc.format.extent10
dc.language.isoeng
dc.relation.ispartofAge and Ageingen
dc.rightsThis is a pre-copyedited, author-produced version of an article accepted for publication in Age and Ageing following peer review. The version of record O'Mahony etal. Prevention of adverse drug reactions in hospitalized older patients with multi-morbidity and polypharmacy: the SENATOR* randomized controlled clinical trial, Age and Ageing, Volume 49, Issue 4, July 2020, Pages 605–614, is available online at: https://doi.org/10.1093/ageing/afaa072.en
dc.subjectadverse drug reactionsen
dc.subjectolder peopleen
dc.subjectmulti-morbidityen
dc.subjectpolypharmacyen
dc.subjectpreventionen
dc.subjectSTOPP/START criteriaen
dc.subjectSoftwareen
dc.subjectsoftwareen
dc.subjectRISK-FACTORSen
dc.subjectEVENTSen
dc.subjectADULTSen
dc.subjectINPATIENTSen
dc.subjectRIGHT TREATMENT CRITERIAen
dc.subjectINTERVENTIONSen
dc.subjectPHARMACISTen
dc.subjectSCREENING TOOLen
dc.subjectQUALITY-OF-LIFEen
dc.subjectELDERLY-PATIENTSen
dc.subjectAdverse drug reactionsen
dc.subjectPreventionen
dc.subjectPolypharmacyen
dc.subjectOlder peopleen
dc.subjectMulti-morbidityen
dc.subjectR Medicineen
dc.subjectGeriatrics and Gerontologyen
dc.subjectAgeingen
dc.subjectEuropean Commissionen
dc.subject(FP7/2007-2013) (grant number 305930)en
dc.subject.lccRen
dc.titlePrevention of Adverse Drug Reactions in Hospitalized Older Patients with Multi-morbidity and Polypharmacy : the SENATOR randomized controlled clinical trialen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Health Services Research Uniten
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPostprinten
dc.description.versionPostprinten
dc.description.versionPostprinten
dc.identifier.doihttps://doi.org/10.1093/ageing/afaa072
dc.date.embargoedUntil2021-06-02
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85087530568&partnerID=8YFLogxKen
dc.identifier.vol49en
dc.identifier.iss4en


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