Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

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Kanoni , S , Graham , S E , Wang , Y , Surakka , I , Ramdas , S , Zhu , X , Clarke , S L , Bhatti , K F , Vedantam , S , Winkler , T W , Locke , A E , Marouli , E , Zajac , G J M , Wu , K-H H , Ntalla , I , Hui , Q , Klarin , D , Hilliard , A T , Wang , Z , Xue , C , Thorleifsson , G , Helgadottir , A , Gudbjartsson , D F , Holm , H , Olafsson , I , Hwang , M Y , Han , S , Akiyama , M , Sakaue , S , Terao , C , Kanai , M , Zhou , W , Brumpton , B M , Rasheed , H , Havulinna , A S , Veturi , Y , Pacheco , J A , Rosenthal , E A , Lingren , T , Feng , Q , Kullo , I J , Narita , A , Takayama , J , Martin , H C , Hunt , K A , Trivedi , B , Haessler , J , Giulianini , F , Bradford , Y , Miller , J E , Campbell , A , Lin , K , Millwood , I Y , Rasheed , A , Hindy , G , Faul , J D , Zhao , W , Weir , D R , Turman , C , Huang , H , Graff , M , Choudhury , A , Sengupta , D , Mahajan , A , Brown , M R , Zhang , W , Yu , K , Schmidt , E M , Pandit , A , Gustafsson , S , Yin , X , Luan , J , Zhao , J-H , Matsuda , F , Jang , H-M , Yoon , K , Medina-Gomez , C , Pitsillides , A , Hottenga , J J , Wood , A R , Ji , Y , Gao , Z , Haworth , S , Yousri , N A , Mitchell , R E , Chai , J F , Aadahl , M , Bjerregaard , A A , Yao , J , Manichaikul , A , Hwu , C-M , Hung , Y-J , Warren , H R , Ramirez , J , Bork-Jensen , J , Kårhus , L L , Goel , A , Sabater-Lleal , M , Noordam , R , Mauro , P , Matteo , F , McDaid , A F , Marques-Vidal , P , Wielscher , M , Trompet , S , Sattar , N , Møllehave , L T , Munz , M , Zeng , L , Huang , J , Yang , B , Poveda , A , Kurbasic , A , Lamina , C , Forer , L , Scholz , M , Galesloot , T E , Bradfield , J P , Ruotsalainen , S E , Daw , EW , Zmuda , J M , Mitchell , J S , Fuchsberger , C , Christensen , H , Brody , J A , Vazquez-Moreno , M , Feitosa , M F , Wojczynski , M K , Wang , Z , Preuss , M H , Mangino , M , Christofidou , P , Verweij , N , Benjamins , J W , Engmann , J , Tsao , N L , Verma , A , Slieker , R C , Lo , K S , Zilhao , N R , Le , P , Kleber , M E , Delgado , G E , Huo , S , Ikeda , D D , Iha , H , Yang , J , Liu , J , Demirkan , A , Leonard , H L , Marten , J , Frank , M , Schmidt , B , Smyth , L J , Cañadas-Garre , M , Wang , C , Nakatochi , M , Wong , A , Hutri-Kähönen , N , Sim , X , Xia , R , Huerta-Chagoya , A , Fernandez-Lopez , J C , Lyssenko , V , Nongmaithem , S S , Bayyana , S , Stringham , H M , Irvin , M R , Oldmeadow , C , Kim , H-N , Ryu , S , Timmers , P R H J , Arbeeva , L , Dorajoo , R , Lange , L A , Prasad , G , Lorés-Motta , L , Pauper , M , Long , J , Li , X , Theusch , E , Takeuchi , F , Spracklen , C N , Loukola , A , Bollepalli , S , Warner , S C , Wang , Y X , Wei , W B , Nutile , T , Ruggiero , D , Sung , Y J , Chen , S , Liu , F , Yang , J , Kentistou , K A , Banas , B , Nardone , G G , Meidtner , K , Bielak , L F , Smith , J A , Hebbar , P , Farmaki , A-E , Hofer , E , Lin , M , Concas , M P , Vaccargiu , S , van der Most , P J , Pitkänen , N , Cade , B E , van der Laan , S W , Chitrala , K N , Weiss , S , Bentley , A R , Doumatey , A P , Adeyemo , A A , Lee , J Y , Petersen , E R B , Nielsen , A A , Choi , H S , Nethander , M , Freitag-Wolf , S , Southam , L , Rayner , N W , Wang , C A , Lin , S-Y , Wang , J-S , Couture , C , Lyytikäinen , L-P , Nikus , K , Cuellar-Partida , G , Vestergaard , H , Hidalgo , B , Giannakopoulou , O , Cai , Q , Obura , M O , van Setten , J , Li , X , Liang , J , Tang , H , Terzikhan , N , Shin , J H , Jackson , R D , Reiner , A P , Martin , L W , Chen , Z , Li , L , Kawaguchi , T , Thiery , J , Bis , J C , Launer , L J , Li , H , Nalls , M A , Raitakari , O T , Ichihara , S , Wild , S H , Nelson , C P , Campbell , H , Jäger , S , Nabika , T , Al-Mulla , F , Niinikoski , H , Braund , P S , Kolcic , I , Kovacs , P , Giardoglou , T , Katsuya , T , de Kleijn , D , de Borst , G J , Kim , E K , Adams , H H H , Ikram , M A , Zhu , X , Asselbergs , F W , Kraaijeveld , A O , Beulens , J W J , Shu , X-O , Rallidis , L S , Pedersen , O , Hansen , T , Mitchell , P , Hewitt , A W , Kähönen , M , Pérusse , L , Bouchard , C , Tönjes , A , Chen , Y-D I , Pennell , C E , Mori , T A , Lieb , W , Franke , A , Ohlsson , C , Mellström , D , Cho , Y S , Lee , H , Yuan , J-M , Koh , W-P , Rhee , S Y , Woo , J-T , Heid , I M , Stark , K J , Zimmermann , M E , Völzke , H , Homuth , G , Evans , M K , Zonderman , A B , Polasek , O , Pasterkamp , G , Hoefer , I E , Redline , S , Pahkala , K , Oldehinkel , A J , Snieder , H , Biino , G , Schmidt , R , Schmidt , H , Bandinelli , S , Dedoussis , G , Thanaraj , T A , Kardia , S L R , Peyser , P A , Kato , N , Schulze , M B , Girotto , G , Böger , C A , Jung , B , Joshi , P K , Bennett , D A , De Jager , P L , Lu , X , Mamakou , V , Brown , M , Caulfield , M J , Munroe , P B , Guo , X , Ciullo , M , Jonas , J B , Samani , N J , Kaprio , J , Pajukanta , P , Tusié-Luna , T , Aguilar-Salinas , C A , Adair , L S , Bechayda , S A , de Silva , H J , Wickremasinghe , A R , Krauss , R M , Wu , J-Y , Zheng , W , Hollander , A I , Bharadwaj , D , Correa , A , Wilson , J G , Lind , L , Heng , C-K , Nelson , A E , Golightly , Y M , Wilson , J F , Penninx , B , Kim , H-L , Attia , J , Scott , R J , Rao , D C , Arnett , D K , Hunt , S C , Walker , M , Koistinen , H A , Chandak , G R , Mercader , J M , Costanzo , M C , Jang , D , Burtt , N P , Villalpando , C G , Orozco , L , Fornage , M , Tai , ES , van Dam , R M , Lehtimäki , T , Chaturvedi , N , Yokota , M , Liu , J , Reilly , D F , McKnight , A J , Kee , F , Jöckel , K-H , McCarthy , M I , Palmer , C N A , Vitart , V , Hayward , C , Simonsick , E , van Duijn , C M , Jin , Z-B , Qu , J , Hishigaki , H , Lin , X , März , W , Gudnason , V , Tardif , J-C , Lettre , G , Hart , L M , Elders , P J M , Damrauer , S M , Kumari , M , Kivimaki , M , van der Harst , P , Spector , T D , Loos , R J F , Province , M A , Parra , E J , Cruz , M , Psaty , B M , Brandslund , I , Pramstaller , P P , Rotimi , C N , Christensen , K , Ripatti , S , Widén , E , Hakonarson , H , Grant , S F A , Kiemeney , L A L M , de Graaf , J , Loeffler , M , Kronenberg , F , Gu , D , Erdmann , J , Schunkert , H , Franks , P W , Linneberg , A , Jukema , J W , Khera , A V , Männikkö , M , Jarvelin , M-R , Kutalik , Z , Francesco , C , Mook-Kanamori , D O , van Dijk , K W , Watkins , H , Strachan , D P , Grarup , N , Sever , P , Poulter , N , Chuang , L-M , Rotter , J I , Dantoft , T M , Karpe , F , Neville , M J , Timpson , N J , Cheng , C-Y , Wong , T-Y , Khor , C C , Li , H , Sabanayagam , C , Peters , A , Gieger , C , Hattersley , A T , Pedersen , N L , Magnusson , P K E , Boomsma , D I , Willemsen , A H M , Cupples , LA , van Meurs , J B J , Ghanbari , M , Gordon-Larsen , P , Huang , W , Kim , Y J , Tabara , Y , Wareham , N J , Langenberg , C , Zeggini , E , Kuusisto , J , Laakso , M , Ingelsson , E , Abecasis , G , Chambers , J C , Kooner , J S , de Vries , P S , Morrison , A C , Hazelhurst , S , Ramsay , M , North , K E , Daviglus , M , Kraft , P , Martin , N G , Whitfield , J B , Abbas , S , Saleheen , D , Walters , R G , Holmes , M V , Black , C , Smith , B H , Baras , A , Justice , A E , Buring , J E , Ridker , P M , Chasman , D I , Kooperberg , C , Tamiya , G , Yamamoto , M , van Heel , D A , Trembath , R C , Wei , W-Q , Jarvik , G P , Namjou , B , Hayes , M G , Ritchie , M D , Jousilahti , P , Salomaa , V , Hveem , K , Åsvold , B O , Kubo , M , Kamatani , Y , Okada , Y , Murakami , Y , Kim , B-J , Thorsteinsdottir , U , Stefansson , K , Zhang , J , Chen , YE , Ho , Y-L , Lynch , J A , Rader , D J , Tsao , P S , Chang , K-M , Cho , K , O'Donnell , C J , Gaziano , J M , Wilson , P W F , Frayling , T M , Hirschhorn , J N , Kathiresan , S , Mohlke , K L , Sun , Y V , Morris , A P , Boehnke , M , Brown , C D , Natarajan , P , Deloukas , P , Willer , C J , Assimes , T L & Peloso , G M 2022 , ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ' , Genome Biology , vol. 23 , no. 1 , 268 . https://doi.org/10.1186/s13059-022-02837-1
URI
https://hdl.handle.net/2164/20148
DOI
https://doi.org/10.1186/s13059-022-02837-1
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