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      Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

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      Bergamaschi_etal_I_Longitudinal_Analysis_Reveals_VOR.pdf (4.204Mb)
      Publication date
      08/06/2021
      Author
      Bergamaschi, Laura
      Mescia, Federica
      Turner, Lorinda
      Hanson, Aimee L.
      Kotagiri, Prasanti
      Dunmore, Benjamin J.
      Ruffieux, Hélène
      Sa, Aloka De
      Huhn, Oisín
      Morgan, Michael D.
      Gerber, Pehuén Pereyra
      Wills, Mark R.
      Baker, Stephen
      Calero-Nieto, Fernando J.
      Doffinger, Rainer
      Dougan, Gordon
      Elmer, Anne
      Goodfellow, Ian G.
      Gupta, Ravindra K.
      Hosmillo, Myra
      Hunter, Kelvin
      Kingston, Nathalie
      Lehner, Paul J.
      Matheson, Nicholas J.
      Nicholson, Jeremy K.
      Petrunkina, Anna M.
      Richardson, Sylvia
      Saunders, Caroline
      Thaventhiran, James E.D.
      Toonen, Erik J.M.
      Weekes, Michael P.
      Göttgens, Berthold
      Toshner, Mark
      Hess, Christoph
      Bradley, John R.
      Lyons, Paul A.
      Smith, Kenneth G.C.
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      Citation
      Bergamaschi , L , Mescia , F , Turner , L , Hanson , A L , Kotagiri , P , Dunmore , B J , Ruffieux , H , Sa , A D , Huhn , O , Morgan , M D , Gerber , P P , Wills , M R , Baker , S , Calero-Nieto , F J , Doffinger , R , Dougan , G , Elmer , A , Goodfellow , I G , Gupta , R K , Hosmillo , M , Hunter , K , Kingston , N , Lehner , P J , Matheson , N J , Nicholson , J K , Petrunkina , A M , Richardson , S , Saunders , C , Thaventhiran , J E D , Toonen , E J M , Weekes , M P , Göttgens , B , Toshner , M , Hess , C , Bradley , J R , Lyons , P A & Smith , K G C 2021 , ' Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease ' , Immunity , vol. 54 , no. 6 , pp. 1257-1275.e8 . https://doi.org/10.1016/j.immuni.2021.05.010
      URI
      https://hdl.handle.net/2164/20265
      DOI
      https://doi.org/10.1016/j.immuni.2021.05.010
      Rights
      Crown Copyright ª 2021 Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). ll OPEN ACCESS
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