Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
Citation
Bergamaschi , L , Mescia , F , Turner , L , Hanson , A L , Kotagiri , P , Dunmore , B J , Ruffieux , H , Sa , A D , Huhn , O , Morgan , M D , Gerber , P P , Wills , M R , Baker , S , Calero-Nieto , F J , Doffinger , R , Dougan , G , Elmer , A , Goodfellow , I G , Gupta , R K , Hosmillo , M , Hunter , K , Kingston , N , Lehner , P J , Matheson , N J , Nicholson , J K , Petrunkina , A M , Richardson , S , Saunders , C , Thaventhiran , J E D , Toonen , E J M , Weekes , M P , Göttgens , B , Toshner , M , Hess , C , Bradley , J R , Lyons , P A , Smith , K G C & Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) Covid BioResource Collaboration 2021 , ' Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease ' , Immunity , vol. 54 , no. 6 , pp. 1257-1275.e8 . https://doi.org/10.1016/j.immuni.2021.05.010
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Crown Copyright ª 2021 Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). ll OPEN ACCESS