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dc.contributor.authorCook, Jonathan A.
dc.contributor.authorHislop, Jenni
dc.contributor.authorAltman, Douglas G.
dc.contributor.authorFayers, Peter
dc.contributor.authorBriggs, Andrew H.
dc.contributor.authorRamsay, Craig R.
dc.contributor.authorNorrie, John D.
dc.contributor.authorHarvey, Ian M.
dc.contributor.authorBuckley, Brian
dc.contributor.authorFergusson, Dean
dc.contributor.authorFord, Ian
dc.contributor.authorVale, Luke D.
dc.contributor.authorDELTA group
dc.date.accessioned2015-03-12T10:54:01Z
dc.date.available2015-03-12T10:54:01Z
dc.date.issued2015-01-15
dc.identifier.citationCook , J A , Hislop , J , Altman , D G , Fayers , P , Briggs , A H , Ramsay , C R , Norrie , J D , Harvey , I M , Buckley , B , Fergusson , D , Ford , I , Vale , L D & DELTA group 2015 , ' Specifying the target difference in the primary outcome for a randomised controlled trial : guidance for researchers ' , Trials , vol. 16 , 12 . https://doi.org/10.1186/s13063-014-0526-8en
dc.identifier.issn1745-6215
dc.identifier.otherPURE: 48447060
dc.identifier.otherPURE UUID: 385bb415-d7a2-479d-9733-a739200d282c
dc.identifier.otherWOS: 000348228700001
dc.identifier.otherScopus: 84939147784
dc.identifier.urihttp://hdl.handle.net/2164/4303
dc.descriptionThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Acknowledgements The authors would like to acknowledge the other members of the DELTA group (Kirsten Harrild, Temitope E Adewuyi and Cynthia Fraser) and the advisory group who were involved in the wider project (Adrian Grant and Marion Campbell). Funding was received from the MRC/NIHR Methodology Research Panel which is jointly funded by the MRC (reference number: G0902147) and Health Technology Assessment (HTA) (project number: 06/98/01). Jonathan Cook held MRC training (reference number: G0601938) and methodology (reference number: G1002292) fellowships while this research was undertaken. The Health Services Research Unit, Institute of Applied Health Sciences (University of Aberdeen), is core-funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorates. The funders had no involvement in study design, collection, analysis and interpretation of data, reporting or the decision to publish.en
dc.format.extent7
dc.language.isoeng
dc.relation.ispartofTrialsen
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en
dc.subjecttarget differenceen
dc.subjectclinically important differenceen
dc.subjectsample sizeen
dc.subjectrandomised controlled trialen
dc.subjectguidanceen
dc.subjectsample-size calculationen
dc.subjectmacular holeen
dc.subjectarterial revascularizationen
dc.subjectstatementen
dc.subjectsurgeryen
dc.subjectsurvivalen
dc.subjectprotocolen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titleSpecifying the target difference in the primary outcome for a randomised controlled trial : guidance for researchersen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Health Services Research Uniten
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Public Health, Health Services and Primary Careen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1186/s13063-014-0526-8


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