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dc.contributor.authorDrake, Amanda J
dc.contributor.authorO'Shaughnessy, Peter J
dc.contributor.authorBhattacharya, Siladitya
dc.contributor.authorMonteiro, Ana
dc.contributor.authorKerrigan, David
dc.contributor.authorGoetz, Sven
dc.contributor.authorRaab, Andrea
dc.contributor.authorRhind, Stewart M
dc.contributor.authorSinclair, Kevin D
dc.contributor.authorMeharg, Andrew A
dc.contributor.authorFeldmann, Jörg
dc.contributor.authorFowler, Paul A
dc.date.accessioned2016-05-02T11:00:16Z
dc.date.available2016-05-02T11:00:16Z
dc.date.issued2015-01-29
dc.identifier.citationDrake , A J , O'Shaughnessy , P J , Bhattacharya , S , Monteiro , A , Kerrigan , D , Goetz , S , Raab , A , Rhind , S M , Sinclair , K D , Meharg , A A , Feldmann , J & Fowler , P A 2015 , ' In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver ' , BMC medicine , vol. 13 , 18 . https://doi.org/10.1186/s12916-014-0251-xen
dc.identifier.issn1741-7015
dc.identifier.otherPURE: 46943152
dc.identifier.otherPURE UUID: 9d360ac7-7095-4b66-bae5-aaa22bb73fff
dc.identifier.otherPubMed: 25630355
dc.identifier.otherScopus: 84924085458
dc.identifier.otherORCID: /0000-0002-4831-9075/work/32997423
dc.identifier.otherORCID: /0000-0002-0524-8254/work/31459809
dc.identifier.otherORCID: /0000-0003-2058-0105/work/72631101
dc.identifier.urihttp://hdl.handle.net/2164/5949
dc.descriptionThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Acknowledgements: We thank Ms Margaret Fraser, Ms Samantha Flannigan, and Dr Wing Yee Kwong for their expert assistance. The staff at Grampian NHS Pregnancy Counselling Service were essential for collecting fetuses. We thank Professor Geoffrey Hammond and Dr Marc Simard, University of British Colombia for helpful comments on the manuscript. Supported by grants as follows: Scottish Senior Clinical Fellowship (AJD); Chief Scientist Office (Scottish Executive, CZG/1/109 to PAF, & CZG/4/742 (PAF & PJOS); NHS Grampian Endowments 08/02 (PAF, SB & PJOS); the European Community’s Seventh Framework Programme (FP7/2007-2013) under grant agreement no 212885 (PAF & SMR); the Medical Research Council grants MR/L010011/1 (PAF & PJOS) and MR/K018310/1 (AJD). None of the funding bodies played any role in the design, collection, analysis, and interpretation of data, in the writing of the manuscript, nor in the decision to submit the manuscript for publicationen
dc.language.isoeng
dc.relation.ispartofBMC medicineen
dc.rights© 2015 Drake et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en
dc.subjectDNA methylationen
dc.subjectliveren
dc.subjectmaternal smokingen
dc.subjectvitamin B12en
dc.subjectR Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/L010011/1en
dc.subjectMR/K018310/1en
dc.subjectChief Scientist Office (CSO)en
dc.subjectCZG/1/109en
dc.subjectCZG/4/742en
dc.subject.lccRen
dc.titleIn utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liveren
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Data Safe Havenen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Energyen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistry (Research Theme)en
dc.contributor.institutionUniversity of Aberdeen.Clinical Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1186/s12916-014-0251-x


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