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Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules

dc.contributor.authorNakamura, Yukio
dc.contributor.authorde Paiva Alves, Eduardo
dc.contributor.authorVeenstra, Gert Jan C.
dc.contributor.authorHoppler, Stefan
dc.date.accessioned2016-06-20T11:40:04Z
dc.date.available2016-06-20T11:40:04Z
dc.date.issued2016-06-01
dc.identifier.citationNakamura , Y , de Paiva Alves , E , Veenstra , G J C & Hoppler , S 2016 , ' Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules ' , Development , vol. 143 , no. 11 , pp. 1914-1925 . https://doi.org/10.1242/dev.131664en
dc.identifier.issn0950-1991
dc.identifier.otherPURE: 64723369
dc.identifier.otherPURE UUID: 8463a8bb-ff3d-48b2-8648-14576ed718e5
dc.identifier.otherScopus: 84973578439
dc.identifier.urihttp://hdl.handle.net/2164/6132
dc.descriptionAcknowledgements We thank Saartje Hontelez (Radboud University, Nijmegen), Sylvie Janssens and Kris Vleminckx (Vlaams Instituut voor Biotechnologie, Universiteit Gent) and Shelby Blythe (Princeton University) for advice on ChIP experiments; Caroline Hill (CRUK, LRI) for discussion on BMP signalling; Juan Larraín (Pontificia Universitad Católica de Chile) and Susan Fairley (European Bioinformatics Institute) for advice on RNA-seq experiments; Yvonne Turnbull (IMSARU, University of Aberdeen) for technical assistance; Alasdair MacKenzie (University of Aberdeen) for discussion and suggestions on the manuscript; Hajime Ogino (Nagahama Institute of Bio-Science and Technology) and Atsushi Suzuki (Hiroshima University) for plasmids; Pierre McCrea (University of Texas MD Anderson Cancer Center) for anti-Xenopus β-catenin antibody; The Genome Analysis Centre (TGAC, BBSRC, Norwich) for high-throughput sequencing; and Xenbase (http://www.xenbase.org) for reference database access. Funding This work was supported by the Biotechnology and Biological Sciences Research Council [BB/I003746/1 to S.H., BB/M001695/1 to S.H. and Y.N.]. Deposited in PMC for immediate release.en
dc.format.extent12
dc.language.isoeng
dc.relation.ispartofDevelopmenten
dc.rights© 2016. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectWnt signallingen
dc.subjectβ-cateninen
dc.subjectXenopusen
dc.subjectGastrulaen
dc.subjectChIP-seqen
dc.subjectRNA-seqen
dc.subjectR Medicineen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/I003746/1en
dc.subjectBB/M001695/1en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleTissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modulesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1242/dev.131664
dc.identifier.vol143en
dc.identifier.iss11en


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