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Biosynthesis of Neocarazostatin A Reveals the Sequential Carbazole Prenylation and Hydroxylation in the Tailoring Steps

dc.contributor.authorHuang, Sheng
dc.contributor.authorElsayed, Somayah Sameer
dc.contributor.authorLv, Meinan
dc.contributor.authorTabudravu, Jioji
dc.contributor.authorRateb, Mostafa E
dc.contributor.authorGyampoh, Roland
dc.contributor.authorKyeremeh, Kwaku
dc.contributor.authorEbel, Rainer
dc.contributor.authorJaspars, Marcel
dc.contributor.authorDeng, Zixin
dc.contributor.authorYu, Yi
dc.contributor.authorDeng, Hai
dc.date.accessioned2016-12-18T00:30:10Z
dc.date.available2016-12-18T00:30:10Z
dc.date.issued2015-12-17
dc.identifier.citationHuang , S , Elsayed , S S , Lv , M , Tabudravu , J , Rateb , M E , Gyampoh , R , Kyeremeh , K , Ebel , R , Jaspars , M , Deng , Z , Yu , Y & Deng , H 2015 , ' Biosynthesis of Neocarazostatin A Reveals the Sequential Carbazole Prenylation and Hydroxylation in the Tailoring Steps ' , Chemistry & Biology , vol. 22 , no. 12 , pp. 1633-1642 . https://doi.org/10.1016/j.chembiol.2015.10.012en
dc.identifier.issn1074-5521
dc.identifier.otherPURE: 59328807
dc.identifier.otherPURE UUID: f9cce7df-47da-4f82-84e6-84096e13ae81
dc.identifier.otherScopus: 84950301578
dc.identifier.otherORCID: /0000-0002-0047-0622/work/32230532
dc.identifier.urihttp://hdl.handle.net/2164/7887
dc.descriptionAcknowledgments Y.Y. acknowledges the financial support from “973” Program (2012CB721006) and National Natural Science Foundation of China (31570033). R.E., K.K., H.D., and M.J. acknowledge the financial support of the Leverhulme Trust-Royal Society Africa Award (AA090088).en
dc.format.extent10
dc.language.isoeng
dc.relation.ispartofChemistry & Biologyen
dc.rights© 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectcarbazole alkaloidsen
dc.subjectbiosynthesisen
dc.subjectprenyltransferaseen
dc.subjectreconstitutionen
dc.subjectP450 enzymeen
dc.subjectneocarazostatin Aen
dc.subjectQ Scienceen
dc.subject.lccQen
dc.titleBiosynthesis of Neocarazostatin A Reveals the Sequential Carbazole Prenylation and Hydroxylation in the Tailoring Stepsen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Natural & Computing Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.description.statusPeer revieweden
dc.description.versionPostprinten
dc.identifier.doihttps://doi.org/10.1016/j.chembiol.2015.10.012
dc.date.embargoedUntil2016-12-17
dc.identifier.vol22en
dc.identifier.iss12en


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