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Elevated catalase expression in a fungal pathogen is a double-edged sword of iron

dc.contributor.authorPradhan, Arnab
dc.contributor.authorHerrero De Dios, Carmen
dc.contributor.authorBelmonte, Rodrigo
dc.contributor.authorBudge, Susan
dc.contributor.authorLopez Garcia, Angela
dc.contributor.authorKolmogorova, Aljona
dc.contributor.authorLEE, Keunsook K
dc.contributor.authorMartin, Brennan D
dc.contributor.authorRibeiro, Antonio
dc.contributor.authorBebes, Attila
dc.contributor.authorYuecel, Raif
dc.contributor.authorGow, Neil A R
dc.contributor.authorMunro, Carol A
dc.contributor.authorMacCallum, Donna M
dc.contributor.authorQuinn, Janet
dc.contributor.authorBrown, Alistair J P
dc.date.accessioned2017-05-23T11:00:18Z
dc.date.available2017-05-23T11:00:18Z
dc.date.issued2017-05-22
dc.identifier.citationPradhan , A , Herrero De Dios , C , Belmonte , R , Budge , S , Lopez Garcia , A , Kolmogorova , A , LEE , K K , Martin , B D , Ribeiro , A , Bebes , A , Yuecel , R , Gow , N A R , Munro , C A , MacCallum , D M , Quinn , J & Brown , A J P 2017 , ' Elevated catalase expression in a fungal pathogen is a double-edged sword of iron ' , PLoS Pathogens , vol. 13 , no. 5 , 1006405 , pp. 1-25 . https://doi.org/10.1371/journal.ppat.1006405en
dc.identifier.issn1553-7366
dc.identifier.otherPURE: 100863181
dc.identifier.otherPURE UUID: 1de1f621-ea58-4953-843d-4798f4409b06
dc.identifier.otherPubMed: 28542620
dc.identifier.otherScopus: 85020214156
dc.identifier.otherORCID: /0000-0003-4833-0378/work/47631118
dc.identifier.urihttp://hdl.handle.net/2164/8675
dc.descriptionWe thank our colleagues in the Aberdeen Fungal Group, Lloyd Peck (British Antarctic Survey) and John Helmann (Cornell University) for insightful discussions. We thank Christophe d’Enfert and Melanie Legrand (Institut Pasteur) for help with the design of barcodes and provision of the CIp10-PTET-GTw overexpression vector and CEC2908 strain. We are grateful to the following Core Facilities at the University of Aberdeen for their excellent technical assistance, advice and support: the Medical Research Facility; the Centre for Genome Enabled Biology and Medicine; the Iain Fraser Cytometry Centre; the Microscopy and Histology Facility; Aberdeen Proteomics; and the qPCR Facility.en
dc.format.extent25
dc.language.isoeng
dc.relation.ispartofPLoS Pathogensen
dc.rightsCopyright: © 2017 Pradhan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. https://creativecommons.org/licenses/by/4.0/en
dc.subjectcandida albicansen
dc.subjectcatalaseen
dc.subjectstress resistanceen
dc.subjectIron homeostasisen
dc.subjectfitnessen
dc.subjecthost colonisationen
dc.subjectvirulenceen
dc.subjectQR Microbiologyen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/F00513X/1en
dc.subjectBB/K017365/1en
dc.subjectBB/K016393/1en
dc.subjectEuropean Research Councilen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/M026663/1en
dc.subjectWellcome Trusten
dc.subject080088en
dc.subject097377en
dc.subject088858/Z/09/Zen
dc.subject.lccQRen
dc.titleElevated catalase expression in a fungal pathogen is a double-edged sword of ironen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.MRC Centre for Medical Mycologyen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1371/journal.ppat.1006405


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