Show simple item record

dc.contributor.authorNeerincx, Andreas
dc.contributor.authorHermann, Clemens
dc.contributor.authorAntrobus, Robin
dc.contributor.authorvan Hateren, Andy
dc.contributor.authorCao, Huan
dc.contributor.authorTrautwein, Nico
dc.contributor.authorStevanović, Stefan
dc.contributor.authorElliott, Tim
dc.contributor.authorDeane, Janet E.
dc.contributor.authorBoyle, Louise H.
dc.date.accessioned2017-06-07T14:12:59Z
dc.date.available2017-06-07T14:12:59Z
dc.date.issued2017-04-20
dc.identifier.citationNeerincx , A , Hermann , C , Antrobus , R , van Hateren , A , Cao , H , Trautwein , N , Stevanović , S , Elliott , T , Deane , J E & Boyle , L H 2017 , ' TAPBPR bridges UDP-glucose : glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway ' , eLife , vol. 6 , e23049 , pp. 1-25 . https://doi.org/10.7554/eLife.23049en
dc.identifier.issn2050-084X
dc.identifier.otherPURE: 100725838
dc.identifier.otherPURE UUID: c1dbe886-f827-47ea-8fe0-629680aaa350
dc.identifier.otherPubMed: 28425917
dc.identifier.otherScopus: 85019455454
dc.identifier.urihttp://hdl.handle.net/2164/8767
dc.descriptionFunding Wellcome: Senior Research Fellowship 104647, Andreas Neerincx, Louise H Boyle Royal Society: University Research Fellowship, UF100371, Janet E Deane Cancer Research UK: Programme Grant, C7056A, Andy van Hateren, Tim Elliott Deutsche Forschungsgemeinschaft: SFB 685, Nico Trautwein, Stefan Stevanović Wellcome: PhD studentship, 089563, Clemens Hermann Wellcome: Strategic Award 100140, Robin Antrobus Wellcome: Programme grant, WT094847MA, Huan Cao Acknowledgements We are extremely grateful to Peter Cresswell and Najla Arshad (Yale University School of Medicine, New Haven, CT) for valuable advice, tapasin and TAP-specific antibody reagents, and the recombinant calreticulin proteins. We thank John Trowsdale (University of Cambridge, UK) for his mentorship and critical reading of this manuscript, and Jim Kaufman (University of Cambridge, UK) for useful discussions. We also thank Yi Cao (Cranfield University, UK) for MATLAB programming for densitometry analysis, and Mark Vickers and Sadie Henderson (Scottish National Blood Transfusion Services, UK) for permitting the use of and assistance with the Amersham WB system. The reagent ARP7099 FEC peptide pool was obtained from the Centre for AIDS Reagents, National Institute for Biological Standards and Control (NIBSC), and was donated by the NIH AIDS Reagent Program, Division of AIDS, NIAID, NIH.en
dc.format.extent25
dc.language.isoeng
dc.relation.ispartofeLifeen
dc.rights© Copyright Neerincx et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited. https://creativecommons.org/licenses/by/4.0/en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectR Medicine (General)en
dc.subjectWellcome Trusten
dc.subject104647en
dc.subject089563en
dc.subject100140en
dc.subjectWT094847MAen
dc.subjectCancer Research UKen
dc.subjectC7056Aen
dc.subject.lccR1en
dc.titleTAPBPR bridges UDP-glucose : glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathwayen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.7554/eLife.23049


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record