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Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies

dc.contributor.authorŠimić, Goran
dc.contributor.authorBabić Leko, Mirjana
dc.contributor.authorWray, Selina
dc.contributor.authorHarrington, Charles
dc.contributor.authorDelalle, Ivana
dc.contributor.authorJovanov-Milošević, Nataša
dc.contributor.authorBažadona, Danira
dc.contributor.authorBuée, Luc
dc.contributor.authorde Silva, Rohan
dc.contributor.authorGiovanni, Giuseppe Di
dc.contributor.authorWischik, Claude
dc.contributor.authorHof, Patrick R.
dc.date.accessioned2017-07-24T14:00:20Z
dc.date.available2017-07-24T14:00:20Z
dc.date.issued2016-03
dc.identifier.citationŠimić , G , Babić Leko , M , Wray , S , Harrington , C , Delalle , I , Jovanov-Milošević , N , Bažadona , D , Buée , L , de Silva , R , Giovanni , G D , Wischik , C & Hof , P R 2016 , ' Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies ' , Biomolecules , vol. 6 , no. 1 , 6 . https://doi.org/10.3390/biom6010006en
dc.identifier.issn2218-273X
dc.identifier.otherPURE: 104706640
dc.identifier.otherPURE UUID: aaafffdd-c7a0-4701-8e5d-006e70669e26
dc.identifier.otherScopus: 85006137585
dc.identifier.otherPubMed: 26751493
dc.identifier.urihttp://hdl.handle.net/2164/8985
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85006137585&partnerID=8YFLogxKen
dc.descriptionAcknowledgments This work was supported by The Croatian Science Foundation grant No. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of potential neuroprotective compounds”) and European Cooperation in Science and Technology (COST) Action CM1103 (“Stucture-based drug design for diagnosis and treatment of neurological diseases: dissecting and modulating complex function in the monoaminergic systems of the brain”). PRH is supported in part by NIH grant P50 AG005138. We also thank Mate Babić for help in preparation of schematics.en
dc.format.extent27
dc.language.isoeng
dc.relation.ispartofBiomoleculesen
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0). https://creativecommons.org/licenses/by/4.0/en
dc.subjectAlzheimer’s diseaseen
dc.subjectAmyloid βen
dc.subjectMicrotubulesen
dc.subjectNeurofibrillary degenerationen
dc.subjectNeuropathologyen
dc.subjectPhosphorylationen
dc.subjectProtein aggregationen
dc.subjectProtein oligomerizationen
dc.subjectTau proteinen
dc.subjectTauopathiesen
dc.subjectR Medicineen
dc.subjectMedicine(all)en
dc.subjectBiochemistryen
dc.subjectMolecular Biologyen
dc.subject.lccRen
dc.titleTau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategiesen
dc.typeJournal itemen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Clinical Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.3390/biom6010006
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85006137585&partnerID=8YFLogxKen


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