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Transporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T cells : Implications for HIV Microbicides

dc.contributor.authorMukhopadhya, Indrani
dc.contributor.authorMurray, Graeme I
dc.contributor.authorDuncan, Linda
dc.contributor.authorYuecel, Raif
dc.contributor.authorShattock, Robin
dc.contributor.authorKelly, Charles
dc.contributor.authorIannelli, Francesco
dc.contributor.authorPozzi, Gianni
dc.contributor.authorEl-Omar, Emad
dc.contributor.authorHold, Georgina
dc.contributor.authorHijazi, Karolin
dc.date.accessioned2017-08-10T15:00:39Z
dc.date.available2017-08-10T15:00:39Z
dc.date.issued2016-09-06
dc.identifier.citationMukhopadhya , I , Murray , G I , Duncan , L , Yuecel , R , Shattock , R , Kelly , C , Iannelli , F , Pozzi , G , El-Omar , E , Hold , G & Hijazi , K 2016 , ' Transporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T cells : Implications for HIV Microbicides ' , Molecular Pharmaceutics , vol. 13 , no. 9 , pp. 3334-3340 . https://doi.org/10.1021/acs.molpharmaceut.6b00351en
dc.identifier.issn1543-8384
dc.identifier.otherPURE: 69579576
dc.identifier.otherPURE UUID: 140d70fc-df46-49e2-b831-af775523e5ca
dc.identifier.otherScopus: 84986320383
dc.identifier.otherORCID: /0000-0002-8589-2129/work/59177110
dc.identifier.otherORCID: /0000-0003-3981-2420/work/76973687
dc.identifier.otherORCID: /0000-0003-2577-518X/work/102536918
dc.identifier.urihttp://hdl.handle.net/2164/9116
dc.descriptionThis work was supported by the European Union's Seventh Framework Programme for research, technological development and demonstration under grant agreement No 305316 as part of the MOTIF (Microbicides Optimisation Through Innovative Formulation for Vaginal and Rectal Delivery) project. We would like to extend our thanks to all the study participants for their invaluable contribution and to Grampian Biorepository staff for help with collection of fresh colorectal resection tissue.en
dc.format.extent7
dc.language.isoeng
dc.relation.ispartofMolecular Pharmaceuticsen
dc.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Molecular Pharmaceutics, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.6b00351en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectefflux drug transportersen
dc.subjectuptake drug transportersen
dc.subjectgene expressionen
dc.subjectCD4+ T cellsen
dc.subjectα4β7 integrinen
dc.subjectcolorectal mucosaen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titleTransporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T cells : Implications for HIV Microbicidesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Dental Educationen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Clinical Medicineen
dc.description.statusPeer revieweden
dc.description.versionPostprinten
dc.identifier.doihttps://doi.org/10.1021/acs.molpharmaceut.6b00351
dc.date.embargoedUntil2017-07-28
dc.identifier.vol13en
dc.identifier.iss9en


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