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Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization

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dc.contributor.authorOueis, Emilia
dc.contributor.authorNardone, Brunello
dc.contributor.authorJaspars, Marcel
dc.contributor.authorWestwood, Nicholas J.
dc.contributor.authorNaismith, James H.
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.date.accessioned2017-02-21T10:28:30Z
dc.date.available2017-02-21T10:28:30Z
dc.date.issued2017-02-01
dc.descriptionAcknowledgements We thank Dr. G. Mann and Dr. A. Bent for supplying the enzymes and the useful discussions, and Dr. T. Lebl for the useful NMR discussions. This work was supported by the European Research Council (339367), UK Biotechnology and Biological Sciences Research Council (K015508/1), the Wellcome Trust [TripleTOF 5600 mass spectrometer (094476), the MALDI TOF-TOF Analyzer (079272AIA), 700 NMR], and the EPSRC UK National Mass Spectrometry Facility at Swansea University. J.H.N., M.A.J., and N.J.W. are named on patents that have been filed by St. Andrews and Aberdeen Universities to commercialize the enzymes (PatG) and (LynD) used in the study. No income derives from the patent.en
dc.description.statusPeer revieweden
dc.format.extent4
dc.format.extent896183
dc.identifier87654263
dc.identifier39295187-9972-46d0-998a-1c2b2c5529fd
dc.identifier85006713711
dc.identifier.citationOueis, E, Nardone, B, Jaspars, M, Westwood, N J & Naismith, J H 2017, 'Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization', ChemistryOpen, vol. 6, no. 1, pp. 11-14. https://doi.org/10.1002/open.201600134en
dc.identifier.doi10.1002/open.201600134
dc.identifier.iss1en
dc.identifier.otherORCID: /0000-0002-2426-6028/work/163664532
dc.identifier.urihttp://hdl.handle.net/2164/8221
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85006713711&partnerID=8YFLogxKen
dc.identifier.vol6en
dc.language.isoeng
dc.relation.ispartofChemistryOpenen
dc.subjectbiotransformationen
dc.subjectcyanobactinen
dc.subjecthybrid macrocyclesen
dc.subjectmacrocyclizationen
dc.subjectpeptidesen
dc.subjectQD Chemistryen
dc.subjectGeneral Chemistryen
dc.subjectEuropean Commissionen
dc.subject339367en
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectK015508/1en
dc.subjectWellcome Trusten
dc.subject094476en
dc.subjectEngineering and Physical Sciences Research Council (EPSRC)en
dc.subject.lccQDen
dc.titleSynthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclizationen
dc.typeJournal itemen

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