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Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis

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dc.contributor.authorYoung, Christine
dc.contributor.authorRussell, John R
dc.contributor.authorvan de Lagemaat, Louie N
dc.contributor.authorLawson, Hannah
dc.contributor.authorMapperley, Christopher
dc.contributor.authorKranc, Kamil R
dc.contributor.authorChristophorou, Maria A
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2023-09-19T14:58:01Z
dc.date.available2023-09-19T14:58:01Z
dc.date.issued2022-06-15
dc.descriptionWe thank the flow cytometry and mouse facilities at the Scottish Centre for Regenerative Medicine. We thank M. Dawson for useful discussions at the conception stage of the project and members of the Christophorou and Kranc labs for critical discussions of the work. Funding: This work was funded by a Wellcome Trust and Royal Society Sir Henry Dale Fellowship to M.A.C. (grant no. 105642/Z/14/Z). K.R.K.’s laboratory is funded by a Cancer Research UK program grant (C29967/A26787) and project grants from the Medical Research Council, Blood Cancer UK, Barts Charity, and the Kay Kendall Leukaemia Fund. Open Access funding provided by Wellcome Trust and Babraham Institute. Deposited in PMC for immediate release.en
dc.description.statusPeer revieweden
dc.format.extent18
dc.format.extent5376485
dc.identifier272590558
dc.identifier32b4ed81-abbf-43ed-b174-e5f481babb6a
dc.identifier35603697
dc.identifier85131902844
dc.identifier.citationYoung, C, Russell, J R, van de Lagemaat, L N, Lawson, H, Mapperley, C, Kranc, K R & Christophorou, M A 2022, 'Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis', Open Biology, vol. 11, no. 6, bio059143. https://doi.org/10.1242/bio.059143en
dc.identifier.doi10.1242/bio.059143
dc.identifier.iss6en
dc.identifier.issn2046-6390
dc.identifier.otherPubMedCentral: PMC9212077
dc.identifier.otherORCID: /0000-0002-2947-1557/work/142978193
dc.identifier.urihttps://hdl.handle.net/2164/21706
dc.identifier.vol11en
dc.language.isoeng
dc.relation.ispartofOpen Biologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectPeptidylarginine deiminase IV (PAD14)en
dc.subjectHaemopoietic developmenten
dc.subjectBone marrowen
dc.subjectDifferentiationen
dc.subjectRegenerationen
dc.subjectAgeingen
dc.subjectR Medicine (General)en
dc.subjectWellcome Trusten
dc.subject105642/Z/14/Zen
dc.subjectCancer Research UKen
dc.subjectC29967/A26787en
dc.subjectMedical Research Council (MRC)en
dc.subject.lccR1en
dc.titleIntrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesisen
dc.typeJournal articleen

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