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Immune cells fold and damage fungal hyphae

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dc.contributor.authorBain, Jude
dc.contributor.authorAlonso, Fernanda
dc.contributor.authorChilders, Delma
dc.contributor.authorWalls, Catriona
dc.contributor.authorMacKenzie, Kevin
dc.contributor.authorPradhan, Arnab
dc.contributor.authorLewis, Leanne E
dc.contributor.authorLouw, Johanna
dc.contributor.authorAvelar, Gabriela M
dc.contributor.authorLarcombe, Daniel E
dc.contributor.authorNetea, Mihai G.
dc.contributor.authorGow, Neil A.R.
dc.contributor.authorBrown, Gordon D
dc.contributor.authorErwig, Lars
dc.contributor.authorBrown, Alistair J.P.
dc.contributor.institutionUniversity of Aberdeen.Company Developmenten
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Epidemiology Groupen
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.date.accessioned2021-04-06T09:57:01Z
dc.date.available2021-04-06T09:57:01Z
dc.date.issued2021-04-13
dc.descriptionAcknowledgements We thank Ben Rutter and Alex Brand for providing Mycelia sterilia hyphae, and Gillian Griffiths for insightful advice. We are grateful to the Microscopy and Histology Core Facility at the University of Aberdeen for their help, advice and support. This work was funded by grants from the UK Medical Research Council [www.mrc.ac.uk], to AJPB, NARG, LPE, MN (MR/M026663/1, MR/M026663/2), and from the University of Aberdeen to AP, DL. The work was also supported by Wellcome [www.wellcome.ac.uk]: NARG, GDB, AJPB (097377); NARG (101873, 200208); and GDB (102705). Further support for this work was also provided by the Medical Research Council Centre for Medical Mycology (MR/N006364/1). MGN was supported by an ERC Advanced Grant (#833247) and a Spinoza grant of the Netherlands Organization for Scientific Research. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en
dc.description.statusPeer revieweden
dc.format.extent8
dc.format.extent1485867
dc.identifier188847312
dc.identifier0d35a2fe-4c2a-48da-8f00-655ee36e29cc
dc.identifier85104246664
dc.identifier.citationBain, J, Alonso, F, Childers, D, Walls, C, MacKenzie, K, Pradhan, A, Lewis, L E, Louw, J, Avelar, G M, Larcombe, D E, Netea, M G, Gow, N A R, Brown, G D, Erwig, L & Brown, A J P 2021, 'Immune cells fold and damage fungal hyphae', PNAS, vol. 118, no. 15, e2020484118. https://doi.org/10.1073/pnas.2020484118en
dc.identifier.doi10.1073/pnas.2020484118
dc.identifier.iss15en
dc.identifier.issn0027-8424
dc.identifier.otherORCID: /0000-0002-0041-5375/work/91891875
dc.identifier.otherORCID: /0000-0003-2869-7332/work/91891878
dc.identifier.otherORCID: /0000-0002-1060-0419/work/112075829
dc.identifier.urihttps://hdl.handle.net/2164/16191
dc.identifier.vol118en
dc.language.isoeng
dc.relation.ispartofPNASen
dc.subjectMacrophagesen
dc.subjectfungal hyphaeen
dc.subjectmechanical forceen
dc.subjectimmunological synapseen
dc.subjectpodosomesen
dc.subjectcytoskeletonen
dc.subjectR Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/M026663/1en
dc.subjectMR/M026663/2en
dc.subjectMR/N006364/1en
dc.subjectEuropean Research Councilen
dc.subject#833247en
dc.subjectWellcome Trusten
dc.subject097377en
dc.subject101873en
dc.subject200208en
dc.subject102705en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleImmune cells fold and damage fungal hyphaeen
dc.typeJournal articleen

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