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Statistical shape modelling provides a responsive measure of morphological change in knee osteoarthritis over 12 months

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dc.contributor.authorGregory, Jennifer S.
dc.contributor.authorBarr, Rebecca J.
dc.contributor.authorYoshida, Kanako
dc.contributor.authorAlesci, Salvatore
dc.contributor.authorReid, David M.
dc.contributor.authorAspden, Richard M.
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)en
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2021-01-14T00:14:17Z
dc.date.available2021-01-14T00:14:17Z
dc.date.embargoedUntil2021-01-14
dc.date.issued2020-09
dc.descriptionFunding: This study was supported by an award (Ref: WHMSB_AU068/071) from the Translational Medicine Research Collaboration (TMRC) – a consortium made up of the Universities of Aberdeen, Dundee, Edinburgh and Glasgow, the four associated NHS Health Boards (Grampian, Tayside, Lothian and Greater Glasgow & Clyde), Scottish Enterprise and initially Wyeth, now Pfizer. The funder had no involvement in the collection, analysis and interpretation of data; in the writing of the manuscript; or in the decision to submit the manuscript for publication. Dr J.S. Gregory was the holder of an MRC New Investigator award (Ref: G0901242). Acknowledgements We are grateful to all the study participants. We thank Lana Gibson and Jennifer Scott for their expertise with the iDXA scanner as well as iDXA precision data and Dr Sandro Galea-Solar for assistance with KL grading.en
dc.description.statusPeer revieweden
dc.format.extent8
dc.format.extent1064700
dc.identifier149393105
dc.identifier26df8072-5e47-4e65-a73a-8ba4530dfaa0
dc.identifier85090076909
dc.identifier000574394600038
dc.identifier.citationGregory, J S, Barr, R J, Yoshida, K, Alesci, S, Reid, D M & Aspden, R M 2020, 'Statistical shape modelling provides a responsive measure of morphological change in knee osteoarthritis over 12 months', Rheumatology, vol. 59, no. 9, pp. 2419-2426. https://doi.org/10.1093/rheumatology/kez610en
dc.identifier.doi10.1093/rheumatology/kez610
dc.identifier.iss9en
dc.identifier.issn1462-0324
dc.identifier.otherSCOPUS: 85090076909
dc.identifier.urihttps://hdl.handle.net/2164/15643
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85090076909&partnerID=8YFLogxKen
dc.identifier.vol59en
dc.language.isoeng
dc.relation.ispartofRheumatologyen
dc.subjectknee osteoarthritisen
dc.subjectstatistical shape modellingen
dc.subjectKellgren-Lawrence gradingen
dc.subjectimaging biomarkeren
dc.subjectreliable changeen
dc.subjectKellgren–Lawrence gradingen
dc.subjectJOINT SPACE WIDTHen
dc.subjectRELIABILITYen
dc.subjectQUANTITATIVE RADIOGRAPHIC FEATURESen
dc.subjectCARTILAGEen
dc.subjectALIGNMENTen
dc.subjectTOTAL HIP-REPLACEMENTen
dc.subjectASSOCIATIONen
dc.subjectPROGRESSIONen
dc.subjectONSETen
dc.subjectR Medicine (General)en
dc.subjectPharmacology (medical)en
dc.subjectRheumatologyen
dc.subjectMedical Research Council (MRC)en
dc.subjectG0901242en
dc.subjectOtheren
dc.subjectWHMSB_AU068/071en
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleStatistical shape modelling provides a responsive measure of morphological change in knee osteoarthritis over 12 monthsen
dc.typeJournal articleen

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