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Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30

dc.contributor.authorHuang, Pei-Ching
dc.contributor.authorHong, Soogil
dc.contributor.authorAlnaser, Hasan F
dc.contributor.authorMimitou, Eleni P
dc.contributor.authorKim, Keun P
dc.contributor.authorMurakami, Hajime
dc.contributor.authorKeeney, Scott
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2024-12-17T17:03:00Z
dc.date.available2024-12-17T17:03:00Z
dc.date.issued2025-01-02
dc.descriptionAcknowledgements This article is subject to the Open Access to Publications policy of the Howard Hughes Medical Institute (HHMI). HHMI lab heads have previously granted a nonexclusive CC BY 4.0 license to the public and a sublicensable license to HHMI in their research articles. Pursuant to those licenses, the author-accepted manuscript of this article can be made freely available under a CC BY 4.0 license immediately upon publication. The authors thank A Viale and N Mohibullah of the Memorial Sloan Kettering Cancer Center (MSK) Integrated Genomics Operation (IGO) for DNA sequencing and N Socci at the MSK Bioinformatics Core Facility for mapping ChIP-seq and S1-seq reads. MSK core facilities are supported by NCI Cancer Center Support Grant P30 CA008748. The IGO was further funded by the Cycle for Survival and the Marie-Josée and Henry R. Kravis Center for Molecular Oncology. The authors thank members of the Keeney laboratory, especially S Yamada for advice on data analysis and S Kim for sharing unpublished information. The authors thank M Lichten for discussion, M Neale and V Garcia for sharing unpublished information, and N Hunter for strains and plasmids. This work was supported by NIH grant R35 GM118092 to SK, National Research Foundation of Korea grant funded by the Korea government (MSIT) 2022M3A9J4079468 to KPK, and Medical Research Council Career Development Award MR/W027313/1 to HM.en
dc.description.statusPeer revieweden
dc.format.extent25
dc.format.extent6225191
dc.identifier299145524
dc.identifier492a1cce-205e-4e92-83a6-4b3bab216bc1
dc.identifier85210582835
dc.identifier85210582835
dc.identifier.citationHuang, P-C, Hong, S, Alnaser, H F, Mimitou, E P, Kim, K P, Murakami, H & Keeney, S 2025, 'Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30', The EMBO Journal, vol. 44, no. 1, pp. 200 - 224. https://doi.org/10.1038/s44318-024-00318-8en
dc.identifier.doi10.1038/s44318-024-00318-8
dc.identifier.iss1en
dc.identifier.otherORCID: /0000-0003-2648-9687/work/172777038
dc.identifier.urihttps://hdl.handle.net/2164/24781
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85210582835&partnerID=8YFLogxKen
dc.identifier.vol44en
dc.language.isoeng
dc.relation.ispartofThe EMBO Journalen
dc.subjectExo1en
dc.subjectFun30en
dc.subjectMeiosisen
dc.subjectRecombinationen
dc.subjectResectionen
dc.subjectR Medicineen
dc.subjectGeneral Neuroscienceen
dc.subjectMolecular Biologyen
dc.subjectGeneral Biochemistry,Genetics and Molecular Biologyen
dc.subjectGeneral Immunology and Microbiologyen
dc.subjectSupplementary Informationen
dc.subjectSupplementary Dataen
dc.subjectGene Expression Omnibus GSE221033en
dc.subjectGene Expression Omnibus GSE52970en
dc.subjectGene Expression Omnibus GSE26452en
dc.subjectGene Expression Omnibus GSE150313en
dc.subjectbiostudies: S-SCDT-10_1038-S44318-024-00318-8en
dc.subject.lccRen
dc.titleMeiotic DNA break resection and recombination rely on chromatin remodeler Fun30en
dc.typeJournal articleen

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