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Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

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dc.contributor.authorLi, Baoguo
dc.contributor.authorLi, Li
dc.contributor.authorLi, Min
dc.contributor.authorLam, Sin Man
dc.contributor.authorWang, Guanlin
dc.contributor.authorWu, Yingga
dc.contributor.authorZhang, Hanlin
dc.contributor.authorNiu, Chaoqun
dc.contributor.authorZhang, Xueying
dc.contributor.authorLiu, Xue
dc.contributor.authorHambly, Catherine
dc.contributor.authorJin, Wanzhu
dc.contributor.authorShui, Guanghou
dc.contributor.authorSpeakman, John R
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Energetics Research Groupen
dc.contributor.institutionUniversity of Aberdeen.Environment and Food Securityen
dc.date.accessioned2019-03-11T14:20:33Z
dc.date.available2019-03-11T14:20:33Z
dc.date.issued2019-03-05
dc.descriptionThis work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and Natural Science Foundation of China (NSFC; 91649108), the Chinese Academy of Sciences-Novo Nordisk Foundation, as well as grants from the Chinese Academy of Sciences “1000 Talents” recruitment program and a “Great-Wall Professorship” from the Chinese Academy of Sciences-Novo Nordisk Foundation. J.R.S. was also supported by a Wolfson merit professorship from The UK Royal Society. We are grateful to all of the members of the Molecular Energetics Group for their support and discussion of the results. We would like to thank Dr. Jia and Dr. Sun from the Core Facility for Protein Research from the Institute of Biophysics, Chinese Academy of Sciences for flow cytometry, and Peter Thomson and Marina Samatiou for technical assistance with the DLW measurements.en
dc.description.statusPeer revieweden
dc.format.extent18
dc.format.extent7955696
dc.identifier142377356
dc.identifier273c4921-787e-45d6-b665-008ce9fdfe61
dc.identifier30840893
dc.identifier85061958692
dc.identifier000460280800017
dc.identifier.citationLi, B, Li, L, Li, M, Lam, S M, Wang, G, Wu, Y, Zhang, H, Niu, C, Zhang, X, Liu, X, Hambly, C, Jin, W, Shui, G & Speakman, J R 2019, 'Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue', Cell Reports, vol. 26, no. 10, pp. 2720-2737. https://doi.org/10.1016/j.celrep.2019.02.015en
dc.identifier.doi10.1016/j.celrep.2019.02.015
dc.identifier.iss10en
dc.identifier.issn2211-1247
dc.identifier.otherMendeley: 0216edde-110e-3e28-b084-22176f5f887a
dc.identifier.urihttp://hdl.handle.net/2164/12030
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85061958692&partnerID=8YFLogxKen
dc.identifier.urlhttp://www.mendeley.com/research/microbiota-depletion-impairs-thermogenesis-brown-adipose-tissue-browning-white-adipose-tissueen
dc.identifier.vol26en
dc.language.isoeng
dc.relation.ispartofCell Reportsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectbrown adipose tissueen
dc.subjectbeige adipocytesen
dc.subjectbrite adipocytesen
dc.subjectwhite adipose tissueen
dc.subjecthermogenesisen
dc.subjectUCP1en
dc.subjectgut microbiotaen
dc.subjectbutyrateen
dc.subjectantibioticsen
dc.subjectgerm free miceen
dc.subjectmacrophageen
dc.subjectIL-4en
dc.subjectCELLSen
dc.subjectCOMMENSAL BACTERIAen
dc.subjectCATECHOLAMINESen
dc.subjectGUT MICROBIOTAen
dc.subjectDIET-INDUCED OBESITYen
dc.subjectALTERNATIVELY ACTIVATED MACROPHAGESen
dc.subjectENERGY-EXPENDITUREen
dc.subjectDEACETYLATIONen
dc.subjectMETABOLISMen
dc.subjectSODIUM-BUTYRATEen
dc.subjectQH301 Biologyen
dc.subjectGeneral Biochemistry,Genetics and Molecular Biologyen
dc.subjectSupplementary Dataen
dc.subjectSupplementary data availableen
dc.subject.lccQH301en
dc.titleMicrobiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissueen
dc.typeJournal articleen

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