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GLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophy

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dc.contributor.authorRoumane, Ahlima
dc.contributor.authorMcilroy, George D
dc.contributor.authorSommer, Nadine
dc.contributor.authorHan, Weiping
dc.contributor.authorHeisler, Lora K
dc.contributor.authorRochford, Justin J
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cardiovascular and Diabetes Centreen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.date.accessioned2024-06-26T13:11:01Z
dc.date.available2024-06-26T13:11:01Z
dc.date.issued2024-04-30
dc.descriptionAcknowledgments The authors would like to thank the staff at the University of Aberdeen’s Microscopy and Histology Core Facility, the Medical Research Facility and Prof. Mirela Delibegovic for technical support and advice with the in vivo studies. The Graphical Abstract was created with BioRender.Com. Ethics statement The animal study was approved by Animal procedures were approved by the University of Aberdeen Ethics Review Board. The study was conducted in accordance with the local legislation and institutional requirements.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent4247631
dc.identifier289739347
dc.identifierc80cbf83-63e1-4ea3-8708-763974c600e4
dc.identifier38745956
dc.identifier85193025729
dc.identifier.citationRoumane, A, Mcilroy, G D, Sommer, N, Han, W, Heisler, L K & Rochford, J J 2024, 'GLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophy', Frontiers in Endocrinology, vol. 15, 1379228. https://doi.org/10.3389/fendo.2024.1379228en
dc.identifier.doi10.3389/fendo.2024.1379228
dc.identifier.issn1664-2392
dc.identifier.otherPubMedCentral: PMC11091257
dc.identifier.otherORCID: /0000-0003-2380-7117/work/162725823
dc.identifier.otherORCID: /0000-0003-4230-4355/work/162726615
dc.identifier.otherORCID: /0000-0002-5020-4939/work/162727005
dc.identifier.urihttps://hdl.handle.net/2164/23717
dc.language.isoeng
dc.relation.ispartofFrontiers in Endocrinologyen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAnimalsen
dc.subjectLiraglutide/pharmacologyen
dc.subjectGlucagon-Like Peptide-1 Receptor/agonistsen
dc.subjectMiceen
dc.subjectMice, Knockouten
dc.subjectDisease Models, Animalen
dc.subjectInsulin Resistanceen
dc.subjectLipodystrophy/drug therapyen
dc.subjectMaleen
dc.subjectMetabolic Diseases/drug therapyen
dc.subjectBlood Glucose/metabolismen
dc.subjectInsulin/metabolismen
dc.subjectHypoglycemic Agents/pharmacologyen
dc.subjectMice, Inbred C57BLen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleGLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophyen
dc.typeJournal articleen

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