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Elevated catalase expression in a fungal pathogen is a double-edged sword of iron

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dc.contributor.authorPradhan, Arnab
dc.contributor.authorHerrero De Dios, Carmen
dc.contributor.authorBelmonte, Rodrigo
dc.contributor.authorBudge, Susan
dc.contributor.authorLopez Garcia, Angela
dc.contributor.authorKolmogorova, Aljona
dc.contributor.authorLEE, Keunsook K
dc.contributor.authorMartin, Brennan D
dc.contributor.authorRibeiro, Antonio
dc.contributor.authorBebes, Attila
dc.contributor.authorYuecel, Raif
dc.contributor.authorGow, Neil A R
dc.contributor.authorMunro, Carol A
dc.contributor.authorMacCallum, Donna M
dc.contributor.authorQuinn, Janet
dc.contributor.authorBrown, Alistair J P
dc.contributor.institutionUniversity of Aberdeen.Centre for Genome-Enabled Biology and Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.MRC Centre for Medical Mycologyen
dc.date.accessioned2017-05-23T11:00:18Z
dc.date.available2017-05-23T11:00:18Z
dc.date.issued2017-05-22
dc.descriptionWe thank our colleagues in the Aberdeen Fungal Group, Lloyd Peck (British Antarctic Survey) and John Helmann (Cornell University) for insightful discussions. We thank Christophe d’Enfert and Melanie Legrand (Institut Pasteur) for help with the design of barcodes and provision of the CIp10-PTET-GTw overexpression vector and CEC2908 strain. We are grateful to the following Core Facilities at the University of Aberdeen for their excellent technical assistance, advice and support: the Medical Research Facility; the Centre for Genome Enabled Biology and Medicine; the Iain Fraser Cytometry Centre; the Microscopy and Histology Facility; Aberdeen Proteomics; and the qPCR Facility.en
dc.description.statusPeer revieweden
dc.format.extent25
dc.format.extent8210632
dc.identifier100863181
dc.identifier1de1f621-ea58-4953-843d-4798f4409b06
dc.identifier28542620
dc.identifier85020214156
dc.identifier.citationPradhan, A, Herrero De Dios, C, Belmonte, R, Budge, S, Lopez Garcia, A, Kolmogorova, A, LEE, K K, Martin, B D, Ribeiro, A, Bebes, A, Yuecel, R, Gow, N A R, Munro, C A, MacCallum, D M, Quinn, J & Brown, A J P 2017, 'Elevated catalase expression in a fungal pathogen is a double-edged sword of iron', PLoS Pathogens, vol. 13, no. 5, 1006405, pp. 1-25. https://doi.org/10.1371/journal.ppat.1006405en
dc.identifier.doi10.1371/journal.ppat.1006405
dc.identifier.iss5en
dc.identifier.issn1553-7366
dc.identifier.otherORCID: /0000-0003-4833-0378/work/47631118
dc.identifier.otherORCID: /0000-0003-0761-1755/work/162728988
dc.identifier.urihttp://hdl.handle.net/2164/8675
dc.identifier.vol13en
dc.language.isoeng
dc.relation.ispartofPLoS Pathogensen
dc.subjectcandida albicansen
dc.subjectcatalaseen
dc.subjectstress resistanceen
dc.subjectIron homeostasisen
dc.subjectfitnessen
dc.subjecthost colonisationen
dc.subjectvirulenceen
dc.subjectQR Microbiologyen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/F00513X/1en
dc.subjectBB/K017365/1en
dc.subjectBB/K016393/1en
dc.subjectEuropean Research Councilen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/M026663/1en
dc.subjectWellcome Trusten
dc.subject080088en
dc.subject097377en
dc.subject088858/Z/09/Zen
dc.subject.lccQRen
dc.titleElevated catalase expression in a fungal pathogen is a double-edged sword of ironen
dc.typeJournal articleen

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