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Processing of Candida albicans Ece1p is critical for Candidalysin maturation and fungal virulence

dc.contributor.authorRichardson, Jonathan P.
dc.contributor.authorMogavero, Selene
dc.contributor.authorMoyes, David L.
dc.contributor.authorBlagojevic, Mariana
dc.contributor.authorKruger, Thomas
dc.contributor.authorVerma, Akash H.
dc.contributor.authorColeman, Bianca M.
dc.contributor.authorDiaz, Jacinto De La Cruz
dc.contributor.authorSchulz, Daniela
dc.contributor.authorPonde, Nicole O.
dc.contributor.authorCarrano, Giulia
dc.contributor.authorKniemeyer, Olaf
dc.contributor.authorWilson, Duncan John
dc.contributor.authorBader, Oliver
dc.contributor.authorEnoui, Simona I.
dc.contributor.authorHo, Jemima Yuer May
dc.contributor.authorKichik, Nessim
dc.contributor.authorGaffen, Sarah L
dc.contributor.authorHube, Bernhard
dc.contributor.authorNaglik, Julian R.
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.MRC Centre for Medical Mycologyen
dc.date.accessioned2018-01-26T14:04:06Z
dc.date.available2018-01-26T14:04:06Z
dc.date.issued2018-01-23
dc.descriptionFunding Information This work was supported by grants from the Biotechnology and Biological Sciences Research Council (BB-J016411-1, BB/N014677/1), Medical Research Council (MR/J008303/1, MR/M011372/1), FP7-PEOPLE-2013-Initial Training Network (606786), Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology (097377/Z/11/Z), and the National Institute for Health Research at Guys and St Thomas's NHS Foundation Trust and King's College London Biomedical Research Centre to JRN; the Leibniz ScienceCampus InfectoOptics SAS-2015- HKI-LWC to BH, the Deutsche Forschungsgemeinschaft (TR/CRC FungiNet, project C1 and Z2) to BH and OK, the Infect ERA-NET Program (FunComPath; BMBF 031L0001A) to BH and SM; and the National Institutes of Health (NIH; DE022550) to SLG. The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication. Acknowledgments We thank Dr. Selvam Thavaraj for helpful discussions and Dr. Sascha Brunke for developing the “Alignator” tool that allowed us to quickly analyse LC-MS/MS output files.en
dc.description.statusPeer revieweden
dc.format.extent1410164
dc.identifier113061682
dc.identifierdeb4142a-bbf5-4029-8f4c-12fd34ade326
dc.identifier85043456981
dc.identifier.citationRichardson, J P, Mogavero, S, Moyes, D L, Blagojevic, M, Kruger, T, Verma, A H, Coleman, B M, Diaz, J D L C, Schulz, D, Ponde, N O, Carrano, G, Kniemeyer, O, Wilson, D J, Bader, O, Enoui, S I, Ho, J Y M, Kichik, N, Gaffen, S L, Hube, B & Naglik, J R 2018, 'Processing of Candida albicans Ece1p is critical for Candidalysin maturation and fungal virulence', mBio, vol. 9, no. 1, e02178-17. https://doi.org/10.1128/mBio.02178-17en
dc.identifier.doi10.1128/mBio.02178-17
dc.identifier.iss1en
dc.identifier.urihttp://hdl.handle.net/2164/9949
dc.identifier.vol9en
dc.language.isoeng
dc.relation.ispartofmBioen
dc.subjectcandida albicansen
dc.subjectcandidalysinen
dc.subjectfungal infectionen
dc.subjectkexinen
dc.subjectmucosal immunityen
dc.subjectR Medicineen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB-J016411-1en
dc.subjectBB/N014677/1en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/J008303/1en
dc.subjectMR/M011372/1en
dc.subjectEuropean Commissionen
dc.subject606786en
dc.subjectWellcome Trusten
dc.subject097377/Z/11/Zen
dc.subjectNational Institute for Health Research (NIHR)en
dc.subject.lccRen
dc.titleProcessing of Candida albicans Ece1p is critical for Candidalysin maturation and fungal virulenceen
dc.typeJournal articleen

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