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Ras hyperactivation versus overexpression : Lessons from Ras dynamics in Candida albicans

dc.contributor.authorPratyusha, Vavilala A
dc.contributor.authorVictoria, Guiliana Soraya
dc.contributor.authorKhan, Mohammad Firoz
dc.contributor.authorHaokip, Dominic T
dc.contributor.authorYadav, Bhawna
dc.contributor.authorPal, Nibedita
dc.contributor.authorSethi, Subhash Chandra
dc.contributor.authorJain, Priyanka
dc.contributor.authorSingh, Sneh Lata
dc.contributor.authorSen, Sobhan
dc.contributor.authorKomath, Sneha Sudha
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2018-05-01T09:13:07Z
dc.date.available2018-05-01T09:13:07Z
dc.date.issued2018
dc.descriptionWe thank Prof. Neta Dean for the CIp10ADH1-Cherry plasmid and Prof. Aaron Mitchell for the BWP17 strain. We gratefully acknowledge Prof. Sudipta Maiti, TIFR, Mumbai, India for providing the data acquisition software. We also appreciate the feedback and discussions with Dr. Rohini Muthuswami, SLS, JNU as well as from the Protein Society group, New Delhi while this study was taking shape. We thank Prof. Alok Bhattacharya for Cytochalasin D. The GC-MS and fluorescence lifetime measurements were carried out at the Advanced Instrumentation Research Facility (AIRF), JNU. Confocal images were recorded either at the central instrumentation facility (CIF), SLS, JNU or at AIRF, JNU. This work was supported by project grants from Department of Biotechnology (DBT, Project grant no. BT/PR20410/BRB/10/1542/2016) and Department of Science and Technology (DST, Project grant no. SB/SO/BB-011/2014), India to S.S.K; and project grants from Department of Information Technology, (DIT, Project grant no. 12(4)/2007-PDD), India to S.S. for FCS setup. In addition, both S.S. and S.S.K. thank DBT-BUILDER for funding support (Project grant no. BT/PR5006/INF/153/2012). S.S.K. also acknowledges funding support from UGC Resource Networking grant to the School of Life Sciences. We thank DST-PURSE and JNU for assistance with funding for publication. G.S.V. and S.C.S. received a fellowship from UGC; V.A.P., B.Y., P.J., N.P., M.F.K. acknowledge CSIR for fellowships. S.L.S. received a fellowship from ICMR. D.T.H. and M.F.K. thank DBT-BUILDER for funding.en
dc.description.statusPeer revieweden
dc.format.extent4400683
dc.identifier119175517
dc.identifierf0324b04-6c0f-4d48-8364-cfa6cc63292e
dc.identifier29588468
dc.identifier85044592246
dc.identifier.citationPratyusha, V A, Victoria, G S, Khan, M F, Haokip, D T, Yadav, B, Pal, N, Sethi, S C, Jain, P, Singh, S L, Sen, S & Komath, S S 2018, 'Ras hyperactivation versus overexpression : Lessons from Ras dynamics in Candida albicans', Scientific Reports, vol. 8, 5248. https://doi.org/10.1038/s41598-018-23187-8en
dc.identifier.doi10.1038/s41598-018-23187-8
dc.identifier.issn2045-2322
dc.identifier.otherPubMedCentral: PMC5869725
dc.identifier.urihttp://hdl.handle.net/2164/10391
dc.identifier.vol8en
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectJournal Articleen
dc.subjectCell signallingen
dc.subjectFluorescence specrometryen
dc.subjectFungal biologyen
dc.subjectMembrane biophysicsen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titleRas hyperactivation versus overexpression : Lessons from Ras dynamics in Candida albicansen
dc.typeJournal articleen

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