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Immune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma : a translational analysis of the DEBIOC clinical trial

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dc.contributor.authorScanlon, E.
dc.contributor.authorLavery, A.
dc.contributor.authorAlbraikat, M.
dc.contributor.authorStevenson, L.
dc.contributor.authorKennedy, C.
dc.contributor.authorByrne, R.
dc.contributor.authorWalker, A.
dc.contributor.authorMullan-Young, B.
dc.contributor.authorMcManus, D. T.
dc.contributor.authorVirdee, P. S.
dc.contributor.authorElhussein, L.
dc.contributor.authorTurbitt, J.
dc.contributor.authorCollinson, D.
dc.contributor.authorMiedzybrodzka, Z.
dc.contributor.authorVan Schaeybroeck, S.
dc.contributor.authorMcQuaid, S.
dc.contributor.authorJames, J. A.
dc.contributor.authorCraig, S. G.
dc.contributor.authorBlayney, J. K.
dc.contributor.authorPetty, R. D.
dc.contributor.authorHarkin, D. P.
dc.contributor.authorKennedy, R. D.
dc.contributor.authorEatock, M. M.
dc.contributor.authorMiddleton, M. R.
dc.contributor.authorThomas, A.
dc.contributor.authorTurkington, R. C.
dc.contributor.institutionUniversity of Aberdeen.Medical Genetics Groupen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2024-12-18T11:58:01Z
dc.date.available2024-12-18T11:58:01Z
dc.date.issued2024-11
dc.descriptionThe authors are grateful for the support of the Northern Ireland Cancer Trials Network, Northern Ireland Biobank, the Belfast Experimental Cancer Medicine Centre and Almac Diagnostics. The DEBIOC study was sponsored by the University of Oxford, with trial management provided by the Oncology Clinical Trials Office. Statistical expertise was provided by the Centre for Statistics in Medicine, Oxford, UK. Preliminary data were presented at the American Society of Clinical Oncology Annual Meeting 2020 (29-31 May 2020, virtual).en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent3060668
dc.identifier298813718
dc.identifier4a8a933e-0895-4424-ad5c-e23d53d8cca8
dc.identifier85206085444
dc.identifier39395265
dc.identifier.citationScanlon, E, Lavery, A, Albraikat, M, Stevenson, L, Kennedy, C, Byrne, R, Walker, A, Mullan-Young, B, McManus, D T, Virdee, P S, Elhussein, L, Turbitt, J, Collinson, D, Miedzybrodzka, Z, Van Schaeybroeck, S, McQuaid, S, James, J A, Craig, S G, Blayney, J K, Petty, R D, Harkin, D P, Kennedy, R D, Eatock, M M, Middleton, M R, Thomas, A & Turkington, R C 2024, 'Immune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma : a translational analysis of the DEBIOC clinical trial', ESMO Open, vol. 9, no. 11, 103930. https://doi.org/10.1016/j.esmoop.2024.103930en
dc.identifier.doi10.1016/j.esmoop.2024.103930
dc.identifier.iss11en
dc.identifier.issn2059-7029
dc.identifier.otherORCID: /0000-0003-2890-8136/work/175113427
dc.identifier.urihttps://hdl.handle.net/2164/24788
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85206085444&partnerID=8YFLogxKen
dc.identifier.vol9en
dc.language.isoeng
dc.relation.ispartofESMO Openen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectadenocarcinomaen
dc.subjectAZD8931en
dc.subjectgene expression signatureen
dc.subjectoesophageal canceren
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectOncologyen
dc.subjectCancer Researchen
dc.subject.lccRC0254en
dc.titleImmune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma : a translational analysis of the DEBIOC clinical trialen
dc.typeJournal articleen

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