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Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation

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dc.contributor.authorSang, Yaqiu
dc.contributor.authorLee, Robert H
dc.contributor.authorLuong, Annie
dc.contributor.authorKatona, Éva
dc.contributor.authorWhyte, Claire S
dc.contributor.authorSmith, Nicholas L
dc.contributor.authorMast, Alan E
dc.contributor.authorFlick, Matthew J
dc.contributor.authorMutch, Nicola J
dc.contributor.authorBergmeier, Wolfgang
dc.contributor.authorWolberg, Alisa S
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2024-10-11T13:34:01Z
dc.date.available2024-10-11T13:34:01Z
dc.date.issued2024-10-08
dc.descriptionThe authors thank László Muszbek for the polyclonal anti-FXIII-Aantibody,Abigail R. Ballardfor technical support, Pablo Ariel for help with the immunofluorescence imaging and analysis, Marina Sokolsky for help with nanoparticle tracking analysis,and Nigel Mackman and Kadri Kangro for reading the manuscript.The Microscopy Services Laboratory, Department of Pathology and Laboratory Medicine, is supported in part by a Cancer Center Core Support Grant to the UNC Lineberger Comprehensive Cancer Center(P30 CA016086).en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent3220706
dc.identifier292647193
dc.identifierf46fb4fb-d6b8-44b6-86b1-6cd463593393
dc.identifier39116293
dc.identifier85206335879
dc.identifier.citationSang, Y, Lee, R H, Luong, A, Katona, É, Whyte, C S, Smith, N L, Mast, A E, Flick, M J, Mutch, N J, Bergmeier, W & Wolberg, A S 2024, 'Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation', Blood Advances, vol. 8, no. 19, 2024012979, pp. 5072–5085. https://doi.org/10.1182/bloodadvances.2024012979en
dc.identifier.doi10.1182/bloodadvances.2024012979
dc.identifier.issn2473-9529
dc.identifier.otherORCID: /0000-0001-8127-6102/work/166226933
dc.identifier.otherORCID: /0000-0002-7452-0813/work/169538857
dc.identifier.urihttps://hdl.handle.net/2164/24380
dc.identifier.urlhttps://www.scopus.com/pages/publications/85206335879en
dc.language.isoeng
dc.relation.ispartofBlood Advancesen
dc.subjectSubstantive link via an eligible employment contracten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectPlatelets and Thrombopoiesisen
dc.subjectThrombosis and Hemostasisen
dc.subjectR Medicine (General)en
dc.subject.lccR1en
dc.titleActivated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradationen
dc.typeJournal articleen

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