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Cereblon E3 Ligase Complex genes are expressed in tissues sensitive to thalidomide in chicken and zebrafish embryos but are unchanged following thalidomide exposure

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dc.contributor.authorRosa Fraga, Lucas
dc.contributor.authorReeves, Jessica
dc.contributor.authorMahony, Christopher
dc.contributor.authorErskine, Lynda
dc.contributor.authorVargesson, Neil
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2025-06-26T07:47:01Z
dc.date.available2025-06-26T07:47:01Z
dc.date.issued2025-06
dc.descriptionOpen access via the Elsevier agreement. The authors thank Shaunna Beedie, Heather Walker, Tiphanie Mérel, Lianne Stevenson, Helena Engman, Zoe Finlayson for producing some of the preliminary data and Alex Diamond and Jonathan Smith for lab assistance and helpful discussions. We also thank Lavinia Schuler-Faccini, Fernanda Sales Luiz Vianna and Thayne Woycinck Kowalski for fruitful discussions. The authors also thank Yvonne Turnbull for zebrafish care and maintenance.en
dc.description.statusPeer revieweden
dc.format.extent15
dc.format.extent14628945
dc.identifier302492141
dc.identifiercd4bcc2c-d644-46bf-97a5-3062ca219fee
dc.identifier105001500590
dc.identifier40158790
dc.identifier.citationRosa Fraga, L, Reeves, J, Mahony, C, Erskine, L & Vargesson, N 2025, 'Cereblon E3 Ligase Complex genes are expressed in tissues sensitive to thalidomide in chicken and zebrafish embryos but are unchanged following thalidomide exposure', Developmental Biology, vol. 522, pp. 156-170. https://doi.org/10.1016/j.ydbio.2025.03.014en
dc.identifier.doi10.1016/j.ydbio.2025.03.014
dc.identifier.issn0012-1606
dc.identifier.otherORCID: /0000-0001-6538-9406/work/186968129
dc.identifier.otherORCID: /0000-0001-8027-114X/work/186968775
dc.identifier.urihttps://hdl.handle.net/2164/25623
dc.identifier.vol522en
dc.language.isoeng
dc.relation.ispartofDevelopmental Biologyen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectAiolosen
dc.subjectIkarosen
dc.subjectCUL4Aen
dc.subjectDDB1en
dc.subjectTeratogenen
dc.subjectThalidomide-induced damageen
dc.subjectQH301 Biologyen
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subject.lccQH301en
dc.titleCereblon E3 Ligase Complex genes are expressed in tissues sensitive to thalidomide in chicken and zebrafish embryos but are unchanged following thalidomide exposureen
dc.typeJournal articleen

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