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Endocytic Sorting and Downregulation of the M2 Acetylcholine Receptor is Regulated by Ubiquitin and the ESCRT Complex

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dc.contributor.authorZenko, Dmitry
dc.contributor.authorThompson, Dawn
dc.contributor.authorHislop, James N.
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.date.accessioned2020-10-21T23:04:46Z
dc.date.available2020-10-21T23:04:46Z
dc.date.embargoedUntil2020-10-22
dc.date.issued2020-01-01
dc.descriptionAcknowledgements The authors would like to thank Professor Mark von Zastrow from the University of California, San Francisco for sharing critical constructs. We would like to thank Kevin MacKenzie and the University of Aberdeen Microscopy core and the Iain Fraser Flow cytometry core for their assistance in the acquisition of data, and Professor Lynda Erskine for critical reading of the manuscript. This work was supported by a PhD studentship from the University of Aberdeen (DZ) and by funding from the Royal Society and Tenovus Scotland (JNH)en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent4919221
dc.identifier148706817
dc.identifier429e1cc7-a46c-4526-9c3b-d7704d54e1b1
dc.identifier31654703
dc.identifier85074165491
dc.identifier.citationZenko, D, Thompson, D & Hislop, J N 2020, 'Endocytic Sorting and Downregulation of the M2 Acetylcholine Receptor is Regulated by Ubiquitin and the ESCRT Complex', Neuropharmacology, vol. 162, 107828. https://doi.org/10.1016/j.neuropharm.2019.107828en
dc.identifier.doi10.1016/j.neuropharm.2019.107828
dc.identifier.issn0028-3908
dc.identifier.otherORCID: /0000-0003-0948-9458/work/77366285
dc.identifier.urihttps://hdl.handle.net/2164/15267
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85074165491&partnerID=8YFLogxKen
dc.identifier.vol162en
dc.language.isoeng
dc.relation.ispartofNeuropharmacologyen
dc.subjectMuscarinic Receptoren
dc.subjectlysosomeen
dc.subjectubiquitinen
dc.subjectendosomeen
dc.subjectESCRTen
dc.subjectrecyclingen
dc.subjectUbiquitinen
dc.subjectLysosomeen
dc.subjectMuscarinic receptoren
dc.subjectRecyclingen
dc.subjectEndosomeen
dc.subjectR Medicine (General)en
dc.subjectCellular and Molecular Neuroscienceen
dc.subjectPharmacologyen
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleEndocytic Sorting and Downregulation of the M2 Acetylcholine Receptor is Regulated by Ubiquitin and the ESCRT Complexen
dc.typeJournal articleen

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