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Microbiota of De-Novo Pediatric IBD : Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis

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dc.contributor.authorHansen, Richard
dc.contributor.authorRussell, Richard K
dc.contributor.authorReiff, Caroline
dc.contributor.authorLouis, Petra
dc.contributor.authorMcIntosh, Freda
dc.contributor.authorBerry, Susan H
dc.contributor.authorMukhopadhya, Indrani
dc.contributor.authorBisset, W Michael
dc.contributor.authorBarclay, Andy R
dc.contributor.authorBishop, Jon
dc.contributor.authorFlynn, Diana M
dc.contributor.authorMcGrogan, Paraic
dc.contributor.authorLoganathan, Sabarinathan
dc.contributor.authorMahdi, Gamal
dc.contributor.authorFlint, Harry J
dc.contributor.authorEl-Omar, Emad M
dc.contributor.authorHold, Georgina L
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.contributor.institutionUniversity of Aberdeen.University of Aberdeenen
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2013-02-14T11:24:00Z
dc.date.available2013-02-14T11:24:00Z
dc.date.issued2012-12-05
dc.descriptionACKNOWLEDGMENTS We are grateful for the expertise of our sequencing provider NewGene and in particular for the support and help of Dr Jonathan Coxhead.Mrs Karen McIntyre and Dr Dagmar Kastner were invaluable in identifying patients for recruitment in Dundee. Mrs Ann Morrice provided administrative support in Aberdeen. Dr Paul Henderson gave helpful comments on the manuscript. We appreciate the generosity of the families who freely gave their time and samples to make this study possible and the theatre staff of all centers who allowed time for sample collection during busy endoscopy lists.en
dc.description.statusPeer revieweden
dc.format.extent10
dc.format.extent288396
dc.identifier20486671
dc.identifier16dd78b5-3ad9-485e-a340-ba0bd646890a
dc.identifier23044767
dc.identifier000312185100021
dc.identifier84870824919
dc.identifier23044767
dc.identifier.citationHansen, R, Russell, R K, Reiff, C, Louis, P, McIntosh, F, Berry, S H, Mukhopadhya, I, Bisset, W M, Barclay, A R, Bishop, J, Flynn, D M, McGrogan, P, Loganathan, S, Mahdi, G, Flint, H J, El-Omar, E M & Hold, G L 2012, 'Microbiota of De-Novo Pediatric IBD : Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis', American journal of gastroenterology, vol. 107, no. 12, pp. 1913-1922. https://doi.org/10.1038/ajg.2012.335en
dc.identifier.doi10.1038/ajg.2012.335
dc.identifier.iss12en
dc.identifier.issn0002-9270
dc.identifier.otherORCID: /0000-0003-2115-2399/work/76973779
dc.identifier.otherORCID: /0000-0003-2577-518X/work/102536900
dc.identifier.urihttp://hdl.handle.net/2164/2662
dc.identifier.vol107en
dc.language.isoeng
dc.relation.ispartofAmerican journal of gastroenterologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectinductionen
dc.subjectinflammatory-bowel-diseaseen
dc.subjecthealthen
dc.subjectfloraen
dc.subjecthuman gut microbiotaen
dc.subjectremissionen
dc.subjectcommunitiesen
dc.subjectnflammatory bowel disease, Crohn's Disease, ulcerative colitisen
dc.subject(Adolescent, Child, Clostridium, Colitis, Ulcerative, Colony Count, Microbial, Crohn Disease, Female, Humans, Inflammatory Bowel Diseases, Male, Real-Time Polymerase Chain Reaction, Journal Article, Research Support, Non-U.S. Gov'ten
dc.subjectRC Internal medicineen
dc.subject.lccRCen
dc.titleMicrobiota of De-Novo Pediatric IBD : Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitisen
dc.typeJournal articleen

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