Lorcaserin improves glycemic control via a melanocortin neurocircuit
| dc.contributor.author | Burke, Luke K. | |
| dc.contributor.author | Ogunnowo-Bada, Emmanuel | |
| dc.contributor.author | Georgescu, Teodora | |
| dc.contributor.author | Cristiano, Claudia | |
| dc.contributor.author | Martinez De Morentin, Pablo B. | |
| dc.contributor.author | Valencia-Torres, Lourdes | |
| dc.contributor.author | D'Agostino, Giuseppe | |
| dc.contributor.author | Riches, Christine | |
| dc.contributor.author | Heeley, Nicholas | |
| dc.contributor.author | Ruan, Yue | |
| dc.contributor.author | Rubinstein, Marcelo | |
| dc.contributor.author | Low, Malcolm J. | |
| dc.contributor.author | Myers, Martin G. | |
| dc.contributor.author | Rochford, Justin J. | |
| dc.contributor.author | Evans, Mark L. | |
| dc.contributor.author | Heisler, Lora K. | |
| dc.contributor.institution | University of Aberdeen.Rowett Institute | en |
| dc.contributor.institution | University of Aberdeen.Medical Education | en |
| dc.contributor.institution | University of Aberdeen.Institute of Applied Health Sciences | en |
| dc.date.accessioned | 2018-01-09T11:33:06Z | |
| dc.date.available | 2018-01-09T11:33:06Z | |
| dc.date.issued | 2017-10-31 | |
| dc.description | Authors wish to thank members of staff of the Medical Research Facility University of Aberdeen, Ms Raffaella Chianese, Ms Pat Bain, Dr Samuel Virtue and Dr Guenievre Roussel for technical assistance. Work was supported by the Wellcome Trust (LKH: WT098012, WT081713; LKH/LKB: 093566/Z/10/A; JJR/GD'A/PBMM: 100574/Z/12/Z), Diabetes UK (MLE: 13/0004680), Biotechnology and Biological Sciences Research Council (LKH: BB/K001418/1, BB/NO17838/1 and JJR: BB/K017772/1), the Medical Research Council (JJR: MR/L002620/1; LKH: MC/PC/15077; GD'A: MR/P009824/1), the Cambridge MRC Centre for Study of Obesity and Related Disorders (MRC-CORD) to LKH, MLE and LKB, European Commission (PBMM/LKH 660219-NeuroEE), Genomics/Transcriptomics Core Facilities, the Neuroscience Graduate Program, the National Institutes of Health (MJL: DK066604; MJL/MR: DK068400; MGM: DK056731) and the Marilyn H. Vincent Foundation to MGM. | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 11 | |
| dc.format.extent | 3617617 | |
| dc.identifier | 104833543 | |
| dc.identifier | a9797ece-5b59-4a7c-83b6-d117a7593cc6 | |
| dc.identifier | 85028336606 | |
| dc.identifier.citation | Burke, L K, Ogunnowo-Bada, E, Georgescu, T, Cristiano, C, Martinez De Morentin, P B, Valencia-Torres, L, D'Agostino, G, Riches, C, Heeley, N, Ruan, Y, Rubinstein, M, Low, M J, Myers, M G, Rochford, J J, Evans, M L & Heisler, L K 2017, 'Lorcaserin improves glycemic control via a melanocortin neurocircuit', Molecular Metabolism, vol. 6, no. 10, pp. 1092-1102. https://doi.org/10.1016/j.molmet.2017.07.004 | en |
| dc.identifier.doi | 10.1016/j.molmet.2017.07.004 | |
| dc.identifier.iss | 10 | en |
| dc.identifier.issn | 2212-8778 | |
| dc.identifier.other | ORCID: /0000-0002-5020-4939/work/53729084 | |
| dc.identifier.uri | http://hdl.handle.net/2164/9877 | |
| dc.identifier.vol | 6 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | Molecular Metabolism | en |
| dc.subject | SDG 3 - Good Health and Well-being | en |
| dc.subject | 5-HT2c receptor | en |
| dc.subject | Type 2 diabetes | en |
| dc.subject | Hypothalamus | en |
| dc.subject | Lorcaserin | en |
| dc.subject | Pro-opiomelanocortin (POMC) | en |
| dc.subject | Melanocortin4 receptor (Mc4r) | en |
| dc.subject | R Medicine (General) | en |
| dc.subject | Wellcome Trust | en |
| dc.subject | WT098012 | en |
| dc.subject | WT081713 | en |
| dc.subject | 093566/Z/10/A | en |
| dc.subject | 100574/Z/12/Z | en |
| dc.subject | Biotechnology and Biological Sciences Research Council (BBSRC) | en |
| dc.subject | BB/K001418/1 | en |
| dc.subject | BB/NO17838/1 | en |
| dc.subject | BB/K017772/1 | en |
| dc.subject | Medical Research Council (MRC) | en |
| dc.subject | MR/L002620/1 | en |
| dc.subject | MC/PC/15077 | en |
| dc.subject | MR/P009824/1 | en |
| dc.subject | European Commission | en |
| dc.subject | 660219-NeuroEE | en |
| dc.subject | Supplementary Data | en |
| dc.subject.lcc | R1 | en |
| dc.title | Lorcaserin improves glycemic control via a melanocortin neurocircuit | en |
| dc.type | Journal article | en |