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A missense mutation in zinc finger homeobox-3 (ZFHX3) impedes growth and alters metabolism and hypothalamic gene expression in mice

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dc.contributor.authorNolan, Patrick M.
dc.contributor.authorBanks, Gareth
dc.contributor.authorBourbia, Nora
dc.contributor.authorWilcox, Ashleigh G.
dc.contributor.authorBentley, Liz
dc.contributor.authorMoir, Lee
dc.contributor.authorKent, Lee
dc.contributor.authorHillier, Rosie
dc.contributor.authorWilson, Dana
dc.contributor.authorBarrett, Perry
dc.contributor.authorDumbell, Rebecca
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2023-10-17T15:09:01Z
dc.date.available2023-10-17T15:09:01Z
dc.date.issued2023-10
dc.descriptionFunding Information: The authors thank the staff of the Mary Lyon Centre and core services at MRC Harwell Institute for assistance with mouse studies. PMN was supported by the Medical Research Council (MC_U142684173), the Barrett lab was supported by the Scottish Government, R. Dumbell was supported by the Medical Research Council (Roger Cox: MC_U142661184) and Nottingham Trent University as well as a Research Visit Grant from the British Society for Neuroendocrinology to carry out this work. A version of this manuscript was previously uploaded to the bioRxiv preprint server.50 The graphical abstract was created with Biorender.com. Publisher Copyright: © 2023 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology.en
dc.description.statusPeer revieweden
dc.format.extent2243098
dc.identifier281621987
dc.identifierc35579af-1372-45c7-92ca-9a6f0a3190d6
dc.identifier85171342644
dc.identifier37713040
dc.identifier.citationNolan, P M, Banks, G, Bourbia, N, Wilcox, A G, Bentley, L, Moir, L, Kent, L, Hillier, R, Wilson, D, Barrett, P & Dumbell, R 2023, 'A missense mutation in zinc finger homeobox-3 (ZFHX3) impedes growth and alters metabolism and hypothalamic gene expression in mice', FASEB JOURNAL, vol. 37, no. 10, e23189. https://doi.org/10.1096/fj.202201829Ren
dc.identifier.doi10.1096/fj.202201829R
dc.identifier.iss10en
dc.identifier.issn0892-6638
dc.identifier.urihttps://hdl.handle.net/2164/21937
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85171342644&partnerID=8YFLogxKen
dc.identifier.vol37en
dc.language.isoeng
dc.relation.ispartofFASEB JOURNALen
dc.subjectappetiteen
dc.subjectatbf1en
dc.subjectenergy balanceen
dc.subjectGpr50en
dc.subjectgrowthen
dc.subjectIGF1en
dc.subjectmouse modelen
dc.subjectsomatostatinen
dc.subjectzfhx3en
dc.subjectQH301 Biologyen
dc.subjectQH426 Geneticsen
dc.subjectBiotechnologyen
dc.subjectBiochemistryen
dc.subjectMolecular Biologyen
dc.subjectGeneticsen
dc.subjectMedical Research Council (MRC)en
dc.subjectMC_U142684173en
dc.subjectMC_U142661184en
dc.subject.lccQH301en
dc.subject.lccQH426en
dc.titleA missense mutation in zinc finger homeobox-3 (ZFHX3) impedes growth and alters metabolism and hypothalamic gene expression in miceen
dc.typeJournal articleen

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