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Modeling Wheezing Spells Identifies Phenotypes with Different Outcomes and Genetic Associates

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dc.contributor.authorHaider, Sadia
dc.contributor.authorGranell, Raquel
dc.contributor.authorCurtin, John
dc.contributor.authorFontanella, Sara
dc.contributor.authorCucco, Alex
dc.contributor.authorTurner, Stephen
dc.contributor.authorSimpson, Angela
dc.contributor.authorRoberts, Graham
dc.contributor.authorMurray, Clare S.
dc.contributor.authorHolloway, John W.
dc.contributor.authorDevereux, Graham
dc.contributor.authorCullinan, Paul
dc.contributor.authorArshad, Syed Hasan
dc.contributor.authorCustovic, Adnan
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Grampian Data Safe Haven (DaSH)en
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.date.accessioned2022-05-13T19:42:01Z
dc.date.available2022-05-13T19:42:01Z
dc.date.issued2022-04-15
dc.descriptionFunding Information: Supported by the UK Medical Research Council (UK MRC) Programme grant MR/S025340/1 and grants G0601361 and MR/K002449/1. R.G. is in part funded through Wellcome Trust Strategic Award 108818/15/Z. The UK MRC and Wellcome (grant ref: 217065/Z/19/Z) and the University of Bristol provide core support for ALSPAC (Avon Longitudinal Study of Parents and Children). MAAS (Manchester Asthma and Allergy Study) was supported by the Asthma UK Grants No 301 (1995–1998), No 362 (1998–2001), No 01/012 (2001–2004), No 04/014 (2004–2007), British Medical Association James Trust (2005), and the JP Moulton Charitable Foundation (2004–2016), the North West Lung Centre Charity (1997–current), and the UK MRC grant MR/L012693/1 (2014–2018). Acknowledgment This article is dedicated to the memory of our wonderful colleague and friend Prof. John Henderson (1958–2019), whose contribution to the understanding of the heterogeneity of childhood asthma cannot be overstated. Rainbow chasers and UNICORN riders forever.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent1009473
dc.identifier215465550
dc.identifier90e54e01-458b-4ce3-a3b6-f2fbe8c5472c
dc.identifier85128493943
dc.identifier35050846
dc.identifier.citationHaider, S, Granell, R, Curtin, J, Fontanella, S, Cucco, A, Turner, S, Simpson, A, Roberts, G, Murray, C S, Holloway, J W, Devereux, G, Cullinan, P, Arshad, S H & Custovic, A 2022, 'Modeling Wheezing Spells Identifies Phenotypes with Different Outcomes and Genetic Associates', American journal of respiratory and critical care medicine, vol. 205, no. 8, pp. 883-893. https://doi.org/10.1164/rccm.202108-1821OCen
dc.identifier.doi10.1164/rccm.202108-1821OC
dc.identifier.issn1073-449X
dc.identifier.urihttps://hdl.handle.net/2164/18561
dc.identifier.urlhttps://www.scopus.com/pages/publications/85128493943en
dc.language.isoeng
dc.relation.ispartofAmerican journal of respiratory and critical care medicineen
dc.subject17q12-21en
dc.subjectasthmaen
dc.subjectgeneticsen
dc.subjectlatent classen
dc.subjectWheezing phenotypesen
dc.subjectR Medicine (General)en
dc.subjectPulmonary and Respiratory Medicineen
dc.subjectCritical Care and Intensive Care Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/S025340/1en
dc.subjectMR/K002449/1en
dc.subjectMR/L012693/1en
dc.subjectWellcome Trusten
dc.subject108818/15/Zen
dc.subject217065/Z/19/Zen
dc.subjectAsthma UKen
dc.subject301 (1995–1998)en
dc.subject362 (1998–2001)en
dc.subject01/012 (2001–2004)en
dc.subject04/014 (2004–2007)en
dc.subjectSupplementary Informationen
dc.subject.lccR1en
dc.titleModeling Wheezing Spells Identifies Phenotypes with Different Outcomes and Genetic Associatesen
dc.typeJournal articleen

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