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A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage

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dc.contributor.authorBernal, Jose
dc.contributor.authorValdés-Hernández, Maria d.C.
dc.contributor.authorEscudero, Javier
dc.contributor.authorHeye, Anna K.
dc.contributor.authorSakka, Eleni
dc.contributor.authorArmitage, Paul A.
dc.contributor.authorMakin, Stephen
dc.contributor.authorTouyz, Rhian M.
dc.contributor.authorWardlaw, Joanna M.
dc.contributor.authorThrippleton, Michael J.
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.date.accessioned2021-02-02T11:40:01Z
dc.date.available2021-02-02T11:40:01Z
dc.date.issued2021-04-15
dc.descriptionAcknowledgements This work is supported by the MRC Doctoral Training Programme in Precision Medicine (JB); the Wellcome Trust (patient recruitment, scanning, and primary study - Reference No. WT088134/Z/09/A); the UK Dementia Research Institute, which receives its funding from DRI Ltd, funded by the UK MRC, Alzheimer’s Society, and Alzheimer’s Research UK; the Fondation Leducq Network for the Study of Perivascular Spaces in Small Vessel Disease (16 CVD 05); The Row Fogo Charitable Trust Centre for Research into ageing and the Brain (MVH) (BRO-D.FID3668413); a British Heart Foundation Chair award (RMT) (CH/12/4/29762); and NHS Lothian Research and Development Office (MJT); European Union Horizon 2020, PHC-03-15, project No666881. We thank the participants, their families, radiographers at Edinburgh Imaging, and the Stroke Research Network at the University of Edinburgh.en
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent5639670
dc.identifier186800566
dc.identifier86d635ea-878f-4688-b606-0c2e8a3cbc09
dc.identifier85100055127
dc.identifier.citationBernal, J, Valdés-Hernández, M D C, Escudero, J, Heye, A K, Sakka, E, Armitage, P A, Makin, S, Touyz, R M, Wardlaw, J M & Thrippleton, M J 2021, 'A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage', Neuroimage, vol. 230, 117786. https://doi.org/10.1016/j.neuroimage.2021.117786en
dc.identifier.doi10.1016/j.neuroimage.2021.117786
dc.identifier.issn1053-8119
dc.identifier.otherRIS: urn:6CDB068283DD6821F1C310FEFE00866D
dc.identifier.otherORCID: /0000-0001-8701-9043/work/88320462
dc.identifier.otherJisc: 381e54e24bc648a2b5e46bf0832a792d
dc.identifier.urihttps://hdl.handle.net/2164/15763
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85100055127&partnerID=8YFLogxKen
dc.identifier.vol230en
dc.language.isoeng
dc.relation.ispartofNeuroimageen
dc.subjectDigital reference objecten
dc.subjectBlood-brain barrier permeabilityen
dc.subjectDCE-MRIen
dc.subjectSpatio-temporal imaging artefactsen
dc.subjectEndothelial dysfunctionen
dc.subjectCerebral small vessel diseaseen
dc.subjectNeurologyen
dc.subjectCognitive Neuroscienceen
dc.subjectR Medicineen
dc.subjectNeurologyen
dc.subjectCognitive Neuroscienceen
dc.subjectOtheren
dc.subjectBRO-D.FID3668413en
dc.subjectBritish Heart Foundationen
dc.subjectCH/12/4/29762en
dc.subjectArthritis Research UK (ARUK)en
dc.subjectWellcome Trusten
dc.subjectWT088134/Z/09/Aen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleA four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakageen
dc.typeJournal articleen

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