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Ligation of newly replicated DNA controls the timing of DNA mismatch repair

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dc.contributor.authorReyes, Gloria X.
dc.contributor.authorKolodziejczak, Anna
dc.contributor.authorDevakumar, Lovely Jael Paul Solomon
dc.contributor.authorKubota, Takashi
dc.contributor.authorKolodner, Richard D.
dc.contributor.authorPutnam, Christopher D.
dc.contributor.authorHombauer, Hans
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2021-03-29T15:44:01Z
dc.date.available2021-03-29T15:44:01Z
dc.date.issued2021-03-22
dc.descriptionAcknowledgments We would like to thank to Dr. Michael Knop for sharing plasmids and infrastructure, for critical comments to the manuscript, and generous support. Thanks to Dr. Hannah Zhao and Dr. Tobias Schmidt for constructing some plasmids/strains used in this study, Dr. Helle Ulrich for valuable discussions and for sharing plasmids (auxin-degron system), and Sandra Ruf and Dr. Nina Papavasiliou for technical support/infrastructure with radioisotopes. R.D.K. and C.D.P. were supported by the NIH grant R01 GM50006 and the Ludwig Institute for Cancer Research. G.X.R., A.K., and H.H. were supported by the Deutsches Krebsforschungszentrum and the Deutsche Forschungsgemeinschaft grant HO-5501-1.en
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent4727586
dc.identifier185424927
dc.identifier746c0824-b16e-4dd9-b0ad-18bfbd56a412
dc.identifier85099677633
dc.identifier33417883
dc.identifier000632826400002
dc.identifier.citationReyes, G X, Kolodziejczak, A, Devakumar, L J P S, Kubota, T, Kolodner, R D, Putnam, C D & Hombauer, H 2021, 'Ligation of newly replicated DNA controls the timing of DNA mismatch repair', Current Biology, vol. 31, no. 6, pp. 1268-1276.E6. https://doi.org/10.1016/j.cub.2020.12.018en
dc.identifier.doi10.1016/j.cub.2020.12.018
dc.identifier.iss6en
dc.identifier.issn0960-9822
dc.identifier.otherRIS: urn:AF8D5DE7D4AF6F066386FE332B6A7159
dc.identifier.otherORCID: /0000-0001-7316-5381/work/88320403
dc.identifier.urihttps://hdl.handle.net/2164/16150
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0960982220318388en
dc.identifier.vol31en
dc.language.isoeng
dc.relation.ispartofCurrent Biologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectmismatch repairen
dc.subjectMMRen
dc.subjectMMR strand discrimination signalen
dc.subjectDNA ligase Ien
dc.subjectDNA ligase I overexpressionen
dc.subjectCdc9en
dc.subjectligation Okazaki fragmentsen
dc.subjectDNA replication-associated nicksen
dc.subjectDNA replication fidelityen
dc.subjectmutation accumulationen
dc.subjectR Medicine (General)en
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleLigation of newly replicated DNA controls the timing of DNA mismatch repairen
dc.typeJournal articleen

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