Polyphosphate co-localizes with factor XII on plateletbound fibrin and augments its plasminogen activator activity
| dc.contributor.author | Mitchell, Joanne L | |
| dc.contributor.author | Lionikiene, Ausra S. | |
| dc.contributor.author | Georgiev, Georgi | |
| dc.contributor.author | Klemmer, Anja | |
| dc.contributor.author | Brain, Chelsea | |
| dc.contributor.author | Kim, Paul Y | |
| dc.contributor.author | Mutch, Nicola J. | |
| dc.contributor.institution | University of Aberdeen.Medicine, Medical Sciences & Nutrition | en |
| dc.contributor.institution | University of Aberdeen.Medical Sciences - Cardiovascular Group | en |
| dc.contributor.institution | University of Aberdeen.Applied Medicine | en |
| dc.contributor.institution | University of Aberdeen.Engineering | en |
| dc.date.accessioned | 2019-05-31T10:00:07Z | |
| dc.date.available | 2019-05-31T10:00:07Z | |
| dc.date.embargoedUntil | 2017-12-15 | |
| dc.date.issued | 2016-12-15 | |
| dc.description | This work was supported by grants FS/11/2/28579 (N.J.M. & A.S.L) from the British Heart Foundation and by the University of Aberdeen Development Trust (J.L.M. & N.J.M.). P.Y.K is supported by an Early Career Award and New Investigator Fund from the Hamilton Health Sciences. We are grateful to the following students for contributions to the project, Natasha Walker & Thomas Nolan. We also thank both the Microscopy and Histology Core Facility and the Iain Fraser Cytometry Centre at the University of Aberdeen for excellent advice and use of the facilities. We also thank Dr Jeffrey Weitz from McMaster University, Canada for the kind gift of HRG. | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 12 | |
| dc.format.extent | 188413 | |
| dc.identifier | 71139719 | |
| dc.identifier | a44e5a45-3295-4ac6-8db0-f082353ad809 | |
| dc.identifier | 27694320 | |
| dc.identifier | 27694320 | |
| dc.identifier | 85014934464 | |
| dc.identifier.citation | Mitchell, J L, Lionikiene, A S, Georgiev, G, Klemmer, A, Brain, C, Kim, P Y & Mutch, N J 2016, 'Polyphosphate co-localizes with factor XII on plateletbound fibrin and augments its plasminogen activator activity', Blood, vol. 128, no. 24, pp. 2834-2845. https://doi.org/10.1182/blood-2015-10-673285 | en |
| dc.identifier.doi | 10.1182/blood-2015-10-673285 | |
| dc.identifier.iss | 24 | en |
| dc.identifier.issn | 0006-4971 | |
| dc.identifier.other | ORCID: /0000-0002-7452-0813/work/169538842 | |
| dc.identifier.uri | http://hdl.handle.net/2164/12341 | |
| dc.identifier.vol | 128 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | Blood | en |
| dc.subject | plasminogen | en |
| dc.subject | factor XII | en |
| dc.subject | polyphosphate | en |
| dc.subject | fibrinolysis | en |
| dc.subject | fibrin | en |
| dc.subject | platelets | en |
| dc.subject | R Medicine | en |
| dc.subject | British Heart Foundation | en |
| dc.subject | FS/11/2/28579 | en |
| dc.subject | Supplementary Data | en |
| dc.subject.lcc | R | en |
| dc.title | Polyphosphate co-localizes with factor XII on plateletbound fibrin and augments its plasminogen activator activity | en |
| dc.type | Journal article | en |