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Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

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dc.contributor.authorNtessalen, Maria
dc.contributor.authorProcter, Nathan Ek
dc.contributor.authorSchwarz, Konstantin
dc.contributor.authorLoudon, Brodie L
dc.contributor.authorMinnion, Magdalena
dc.contributor.authorFernandez, Bernadette O
dc.contributor.authorVassiliou, Vassilios S
dc.contributor.authorVauzour, David
dc.contributor.authorMadhani, Melanie
dc.contributor.authorConstantin-Teodosiu, Dumitru
dc.contributor.authorHorowitz, John D
dc.contributor.authorFeelisch, Martin
dc.contributor.authorDawson, Dana
dc.contributor.authorCrichton, Paul G
dc.contributor.authorFrenneaux, Michael P
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.date.accessioned2019-11-08T11:10:01Z
dc.date.available2019-11-08T11:10:01Z
dc.date.issued2020-01
dc.descriptionSupported by Medical Research Council program grant MRC G1001340 (to M Madhani, M Feelisch, and MP Frenneaux). We thank Lesley Cheyne for their contributions to the present study. The authors’ responsibilities were as follows—VSV, M Madhani, JDH, MF, DD, MPF: designed the research; MN, NEKP, KS, BLL, M Minnion, BOF, DV, DC-T, PGC: conducted the research; DV: provided essential materials; MN, NEKP, M Minnion, BOF, DC-T, MF, PGC: analyzed the data; MN, NEKP, PGC, MPF: wrote the paper; MPF: had primary responsibility for the final manuscript; and all authors: read and approved the final manuscript. None of the authors reported a conflict of interest related to the study.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent2728328
dc.identifier149106379
dc.identifier7709f718-d774-470b-8fef-531a77c0ab42
dc.identifier31599928
dc.identifier85077667635
dc.identifier.citationNtessalen, M, Procter, N E, Schwarz, K, Loudon, B L, Minnion, M, Fernandez, B O, Vassiliou, V S, Vauzour, D, Madhani, M, Constantin-Teodosiu, D, Horowitz, J D, Feelisch, M, Dawson, D, Crichton, P G & Frenneaux, M P 2020, 'Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans', The American Journal of Clinical Nutrition, vol. 111, no. 1, pp. 79-89. https://doi.org/10.1093/ajcn/nqz245en
dc.identifier.doi10.1093/ajcn/nqz245
dc.identifier.iss1en
dc.identifier.issn0002-9165
dc.identifier.otherORCID: /0000-0003-2815-4469/work/160846721
dc.identifier.urihttps://hdl.handle.net/2164/13241
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85077667635&partnerID=8YFLogxKen
dc.identifier.vol111en
dc.language.isoeng
dc.relation.ispartofThe American Journal of Clinical Nutritionen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectnitrateen
dc.subjectnitriteen
dc.subjectmitochondriaen
dc.subjectuncoupling proteinen
dc.subjectpyruvate dehydrogenaseen
dc.subjectuncoupling proteinsen
dc.subjectR Medicineen
dc.subjectNutrition and Dieteticsen
dc.subjectMedicine (miscellaneous)en
dc.subjectMedical Research Council (MRC)en
dc.subjectMRC G1001340en
dc.subject.lccRen
dc.titleInorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humansen
dc.typeJournal articleen

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