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SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication

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dc.contributor.authorConnolly, Caitlin
dc.contributor.authorTakahashi, Saori
dc.contributor.authorMiura, Hisashi
dc.contributor.authorHiratani, Ichiro
dc.contributor.authorGilbert, Nick
dc.contributor.authorDonaldson, Anne
dc.contributor.authorHiraga, Shin-ichiro
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.date.accessioned2022-12-10T00:14:18Z
dc.date.available2022-12-10T00:14:18Z
dc.date.embargoedUntil2022-12-10
dc.date.issued2022-01-24
dc.descriptionFunding CC was supported by a BBSRC EASTBIO Doctoral Training programme PhD studentship. SH was supported by Daiwa Anglo-Japanese Foundation 812 (12928/13746). Work in the Hiraga-Donaldson lab supported by Cancer Research UK awards C1445/A19059 and DRCPGM\100013. NG is supported by Medical Research Council (MC_UU_00007/13) Acknowledgements Information for SAF-A expression was obtained at The Cancer Genome Atlas TCGA) Research Network (https://www.cancer.gov/tcga). We thank Dr Ryu-suke Nozawa for help in the early stage of the project, and Professor Julian Blow for advice on the 3D licensing assay. Thanks to the staff of the Iain Fraser Cytometry Centre, and Microscopy and Histology facility at the University of Aberdeen.en
dc.description.statusPeer revieweden
dc.format.extent15
dc.format.extent7656780
dc.identifier209579956
dc.identifierc95be3aa-9075-4c7f-8640-da14db68df9e
dc.identifier85123746711
dc.identifier.citationConnolly, C, Takahashi, S, Miura, H, Hiratani, I, Gilbert, N, Donaldson, A & Hiraga, S 2022, 'SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication', Journal of Cell Science, vol. 135, no. 2, jcs.258991. https://doi.org/10.1242/jcs.258991en
dc.identifier.doi10.1242/jcs.258991
dc.identifier.iss2en
dc.identifier.issn0021-9533
dc.identifier.otherORCID: /0000-0002-8722-3869/work/104792188
dc.identifier.urihttps://hdl.handle.net/2164/19713
dc.identifier.vol135en
dc.language.isoeng
dc.relation.ispartofJournal of Cell Scienceen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectDNA replicationen
dc.subjectChromatinen
dc.subjectReplication stressen
dc.subjectR Medicineen
dc.subjectCancer Research UKen
dc.subjectC1445/A19059en
dc.subjectDRCPGM\100013en
dc.subjectMedical Research Council (MRC)en
dc.subjectMC_UU_00007/13en
dc.subjectSupplementary Informationen
dc.subject.lccRen
dc.titleSAF-A promotes origin licensing and replication fork progression to ensure robust DNA replicationen
dc.typeJournal articleen

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