University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds : Managing Adolescent first episode Psychosis: a feasibility study (MAPS)

Simple item page
dc.contributor.authorPyle, Melissa
dc.contributor.authorBroome, Matthew R
dc.contributor.authorJoyce, Emmeline
dc.contributor.authorMacLennan, Graeme
dc.contributor.authorNorrie, John
dc.contributor.authorFreeman, Daniel
dc.contributor.authorFowler, David
dc.contributor.authorHaddad, Peter M
dc.contributor.authorShiers, David
dc.contributor.authorHollis, Chris
dc.contributor.authorSmith, Jo
dc.contributor.authorLiew, Ashley
dc.contributor.authorByrne, Rory E
dc.contributor.authorFrench, Paul
dc.contributor.authorPeters, Sarah
dc.contributor.authorHudson, Jemma
dc.contributor.authorDavies, Linda
dc.contributor.authorEmsley, Richard
dc.contributor.authorYung, Alison
dc.contributor.authorBirchwood, Max
dc.contributor.authorLongden, Eleanor
dc.contributor.authorMorrison, Anthony P
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.date.accessioned2019-07-19T13:40:05Z
dc.date.available2019-07-19T13:40:05Z
dc.date.issued2019-07-04
dc.descriptionAcknowledgements Thank you to all the participants, family members/carers who agreed to take part in the trial and clinicians who have supported participant enrolment into the trial. This study was supported by the National Institute for Health Research (NIHR), the NIHR MindTech MedTech Co-operative, the NIHR Nottingham Biomedical Research Centre and the Clinical Research Network-Mental Health. MBi is part funded by NIHR CLAHRC West Midlands. We are grateful to the Psychosis Research Unit (PRU) Service User Reference Group (SURG) for their consultation regarding the design of the study and contribution to the developments of study-related materials. We are grateful to our Independent Trial Steering Committee and Independent Data Monitoring Committee for providing oversight of the trial. Funding MAPS was funded by the NIHR HTA programme (project number 15/31/04) and the final report will be published in Health Technology Assessment. Visit the HTA programme website for further project information. The Sponsor is Greater Manchester Mental Health NHS Foundation Trust, email R&D@gmmh.nhs.uk. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the HTA programme, NIHR, NHS or the Department of Health. Authors’ contributions MP made substantial contribution to the development of the trial protocol and to the overall management of the trial and data management, and wrote the first draft of the manuscript. AL, AY, CH, DFo, DFr, DS, EL, LD, PF, SP, MBi, MBr and REB contributed to the application for funding, made substantial contribution to the design of the trial and protocol and critically read the manuscript. EJ contributed to the writing of the manuscript. GM made substantial contribution to the design of the trial, the protocol and the statistical analysis plan and critically read the manuscript. JN, RE contributed to the application for funding, made substantial contribution to the design of the trial, the protocol and the statistical analysis plan and critically read the manuscript. PH made substantial contribution to the design of the trial and protocol and critically read the manuscript. JS made a substantial contribution to the family intervention component of the protocol, provided FI supervision to therapists on the trial and contributed to the writing of the manuscript. JH made substantial contribution to the statistical analysis plan and critically read the manuscript. APM planned the study, contributed to the application for funding, made substantial contribution to the design of the trial protocol and the statistical analysis plan, managed the stud, and critically read the manuscript. All authors read and approved the final manuscript.en
dc.description.statusPeer revieweden
dc.format.extent795588
dc.identifier145867097
dc.identifier9bc0d72f-2c61-4003-8299-cfad015d563d
dc.identifier31272477
dc.identifier85068571686
dc.identifier.citationPyle, M, Broome, M R, Joyce, E, MacLennan, G, Norrie, J, Freeman, D, Fowler, D, Haddad, P M, Shiers, D, Hollis, C, Smith, J, Liew, A, Byrne, R E, French, P, Peters, S, Hudson, J, Davies, L, Emsley, R, Yung, A, Birchwood, M, Longden, E & Morrison, A P 2019, 'Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds : Managing Adolescent first episode Psychosis: a feasibility study (MAPS)', Trials, vol. 20, 395. https://doi.org/10.1186/s13063-019-3506-1en
dc.identifier.doi10.1186/s13063-019-3506-1
dc.identifier.issn1745-6215
dc.identifier.otherMendeley: 85cfdf96-671f-3cb0-99d3-5566490fe4cb
dc.identifier.otherORCID: /0000-0002-1039-5646/work/98038516
dc.identifier.urihttp://hdl.handle.net/2164/12603
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85068571686&partnerID=8YFLogxKen
dc.identifier.urlhttps://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3506-1en
dc.identifier.urlhttp://www.mendeley.com/research/study-protocol-randomised-controlled-trial-cbt-vs-antipsychotics-vs-both-1418yearolds-managing-adoleen
dc.identifier.vol20en
dc.language.isoeng
dc.relation.ispartofTrialsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectCBTen
dc.subjectantipsychoticsen
dc.subjectpsychosisen
dc.subjectAdolescent psychosisen
dc.subjectFamily interventionen
dc.subjectRandomised controlled trialen
dc.subjectSchizophreniaen
dc.subjectFirst-episode psychosisen
dc.subjectCognitive behavioural therapyen
dc.subjectPsychological interventionen
dc.subjectAntipsychotic medicationen
dc.subjectR Medicineen
dc.subjectPharmacology (medical)en
dc.subjectMedicine (miscellaneous)en
dc.subjectNational Institute for Health Research (NIHR)en
dc.subjectNIHR HTA 15/31/04en
dc.subjectNIHR MindTech MedTech Co-operativeen
dc.subjectNIHR Nottingham Biomedical Research Centreen
dc.subjectClinical Research Network-Mental Healten
dc.subjectNIHR CLAHRC West Midlandsen
dc.subject.lccRen
dc.titleStudy protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds : Managing Adolescent first episode Psychosis: a feasibility study (MAPS)en
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
s13063_019_3506_1.pdf
Size:
776.94 KB
Format:
Adobe Portable Document Format
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
8.3 KB
Format:
Plain Text
Description:
Download

Collections

All research
Applied Health Sciences research
University Office research