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Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON) : a randomised controlled phase III trial

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dc.contributor.authorWhitaker, Lucy H.R.
dc.contributor.authorMiddleton, Lee J.
dc.contributor.authorDaniels, Jane P.
dc.contributor.authorWilliams, Alistair R.W.
dc.contributor.authorPriest, Lee
dc.contributor.authorOdedra, Smita
dc.contributor.authorCheed, Versha
dc.contributor.authorStubbs, Clive E.
dc.contributor.authorClark, T. Justin
dc.contributor.authorLumsden, Mary-Ann
dc.contributor.authorHapangama, Dharani K.
dc.contributor.authorBhattacharya, Siladitya
dc.contributor.authorSmith, Paul P.
dc.contributor.authorNicholls, Elaine P.
dc.contributor.authorRoberts, Neil
dc.contributor.authorSemple, Scott I.
dc.contributor.authorSaraswat, Lucky
dc.contributor.authorWalker, Jane
dc.contributor.authorChodankar, Rohan R.
dc.contributor.authorCritchley, Hilary O.D.
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.University of Aberdeenen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Women’s Health Researchen
dc.date.accessioned2023-05-23T15:12:01Z
dc.date.available2023-05-23T15:12:01Z
dc.date.issued2023-06-01
dc.descriptionAcknowledgments This project was funded by the Efficacy and Mechanism Evaluation programme, a Medical Research Council and National Institute for Health Research partnership (grant 12/206/52). Medical Research Council (MRC) Centre grants to the Centre for Reproductive Health (CRH) (G1002033 and MR/N022556/1) are also gratefully acknowledged. The views expressed in this publication are those of the authors and not necessarily those of the Medical Research Council, National Institute for Health Research, or Department of Health and Social Care. We thank our Collaborative Group (listed in the Supplementary Material) for their contribution to recruitment, randomisation and collection of data, and to our Trial Steering and Data Monitoring Committees (members listed in Supplementary Material).en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent616366
dc.identifier248335741
dc.identifiera939196c-dad5-46bc-8cea-3b22d48d4630
dc.identifier85159567010
dc.identifier.citationWhitaker, L H R, Middleton, L J, Daniels, J P, Williams, A R W, Priest, L, Odedra, S, Cheed, V, Stubbs, C E, Clark, T J, Lumsden, M-A, Hapangama, D K, Bhattacharya, S, Smith, P P, Nicholls, E P, Roberts, N, Semple, S I, Saraswat, L, Walker, J, Chodankar, R R & Critchley, H O D 2023, 'Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON) : a randomised controlled phase III trial', EClinicalMedicine, vol. 60, 101995. https://doi.org/10.1016/j.eclinm.2023.101995en
dc.identifier.doi10.1016/j.eclinm.2023.101995
dc.identifier.issn2589-5370
dc.identifier.otherRIS: urn:9891C79BBBF760CDB7680F460FDC5EBA
dc.identifier.urihttps://hdl.handle.net/2164/20762
dc.identifier.vol60en
dc.language.isoeng
dc.relation.ispartofEClinicalMedicineen
dc.subjectHeavy menstrual bleedingen
dc.subjectUlipristal acetateen
dc.subjectSelective progesterone receptor modulatoren
dc.subjectLevonorgestrel-releasing intrauterine systemen
dc.subjectRandomised controlled trialen
dc.subjectFibroiden
dc.subjectLeiomyomaen
dc.subjectAdenomyosis endometriumen
dc.subjectUterusen
dc.subjectQuality of lifeen
dc.subjectAmenorrhoeaen
dc.subjectUltrasounden
dc.subjectProgesterone receptor modulator associated endometrial changesen
dc.subjectDrug induced liver injuryen
dc.subjectUrgent safety measuresen
dc.subjectR Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subject12/206/52en
dc.subjectG1002033en
dc.subjectMR/N022556/1en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleUlipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON) : a randomised controlled phase III trialen
dc.typeJournal articleen

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