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Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia

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dc.contributor.authorCraig, Stephanie G.
dc.contributor.authorHumphries, Matthew P
dc.contributor.authorAlderdice, Matthew
dc.contributor.authorBingham, Victoria
dc.contributor.authorRichman, Susan D.
dc.contributor.authorLoughrey, Maurice B.
dc.contributor.authorColeman, Helen G
dc.contributor.authorViratham-Pulsawatdi, Amelie
dc.contributor.authorMcCombe, Kris
dc.contributor.authorMurray, Graeme I.
dc.contributor.authorBlake, Andrew
dc.contributor.authorDomingo, Enric
dc.contributor.authorRobineau, James
dc.contributor.authorBrown, Louise
dc.contributor.authorFisher, David
dc.contributor.authorSeymour, Matthew T.
dc.contributor.authorQuirke, Phil
dc.contributor.authorBankhead, Peter
dc.contributor.authorMcQuaid, Stephen
dc.contributor.authorLawler, Mark
dc.contributor.authorMcArt, Darragh G.
dc.contributor.authorMaughan, Tim S.
dc.contributor.authorJames, Jacqueline A
dc.contributor.authorSalto-Tellez, Manuel
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2020-10-14T15:44:00Z
dc.date.available2020-10-14T15:44:00Z
dc.date.issued2020-10-13
dc.descriptionAcknowledgements: PQ is a National Institute of Health Research Senior Investigator. Funding: The funders had no role in study design, collection, data analysis, or interpretation of the data. This study was supported by a Cancer Research UK Accelerator grant and carried out in collaboration with the stratified medicine consortium in colorectal cancer (S:CORT) which is jointly funded by the Medical Research Council and Cancer Research UK. Data availability The data are held within the Northern Ireland Biobank and the stratified medicine consortium in colorectal cancer (S:CORT), respectively, and are available on application.en
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent1378794
dc.format.extent1931514
dc.identifier171438281
dc.identifier07396b02-ac5f-4b1c-8ac0-1352bcc56c40
dc.identifier85088133186
dc.identifier32684627
dc.identifier000550125400004
dc.identifier.citationCraig, S G, Humphries, M P, Alderdice, M, Bingham, V, Richman, S D, Loughrey, M B, Coleman, H G, Viratham-Pulsawatdi, A, McCombe, K, Murray, G I, Blake, A, Domingo, E, Robineau, J, Brown, L, Fisher, D, Seymour, M T, Quirke, P, Bankhead, P, McQuaid, S, Lawler, M, McArt, D G, Maughan, T S, James, J A & Salto-Tellez, M 2020, 'Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia', British Journal of Cancer, vol. 123, pp. 1280-1288. https://doi.org/10.1038/s41416-020-0985-5en
dc.identifier.doi10.1038/s41416-020-0985-5
dc.identifier.issn0007-0920
dc.identifier.otherORCID: /0000-0003-3981-2420/work/78069038
dc.identifier.urihttps://hdl.handle.net/2164/15227
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85088133186&partnerID=8YFLogxKen
dc.identifier.vol123en
dc.language.isoeng
dc.relation.ispartofBritish Journal of Canceren
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectCancer microenvironmenten
dc.subjectcolorectal canceren
dc.subjecttumour biomarkersen
dc.subjectMICROENVIRONMENTen
dc.subjectCARCINOMAen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectR Medicineen
dc.subjectOncologyen
dc.subjectCancer Researchen
dc.subjectMedical Research Council (MRC)en
dc.subjectCancer Research UKen
dc.subjectSupplementary Dataen
dc.subject.lccRC0254en
dc.subject.lccRen
dc.titleImmune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxiaen
dc.typeJournal articleen

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