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Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures

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dc.contributor.authorMahmood, Umair
dc.contributor.authorBlake, Andrew
dc.contributor.authorRathee, Sanjay
dc.contributor.authorSamuel, Leslie
dc.contributor.authorMurray, Graeme
dc.contributor.authorSebag-Montefiore, David
dc.contributor.authorGollins, Simon
dc.contributor.authorWest, Nicholas P
dc.contributor.authorBegum, Rubina
dc.contributor.authorBach, Simon P
dc.contributor.authorRichman, Susan D
dc.contributor.authorQuirke, Phil
dc.contributor.authorRedmond, Keara L
dc.contributor.authorSalto-Tellez, Manuel
dc.contributor.authorKoelzer, Viktor H
dc.contributor.authorLeedham, Simon J
dc.contributor.authorTomlinson, Ian
dc.contributor.authorDunne, Philip D
dc.contributor.authorBuffa, Francesca M
dc.contributor.authorMaughan, Tim S
dc.contributor.authorDomingo, Enric
dc.contributor.institutionUniversity of Aberdeen.Administation Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cancer Centreen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2024-07-22T13:01:01Z
dc.date.available2024-07-22T13:01:01Z
dc.date.issued2024-07-18
dc.descriptionAcknowledgments This research from the MRC/CRUK project S:CORT consortium was funded by the UKRI (MR/M016587/1). The ARISTOTLE trial was funded by Cancer Research UK (CRUK/08/032). F.M. Buffa and S. Rathee also received funding from ERC Consolidator Grant 772970 (Micro-C). Members of the S:CORT consortium are listed in the Supplementary Data (S:CORT consortium authors list). For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission.en
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent3468175
dc.identifier291854149
dc.identifier739a9824-36a2-4e93-86e7-1f5380f7f01b
dc.identifier39023969
dc.identifier85198594803
dc.identifier.citationMahmood, U, Blake, A, Rathee, S, Samuel, L, Murray, G, Sebag-Montefiore, D, Gollins, S, West, N P, Begum, R, Bach, S P, Richman, S D, Quirke, P, Redmond, K L, Salto-Tellez, M, Koelzer, V H, Leedham, S J, Tomlinson, I, Dunne, P D, Buffa, F M, Maughan, T S & Domingo, E 2024, 'Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures', Cancer research communications, vol. 4, no. 7, pp. 1765-1776. https://doi.org/10.1158/2767-9764.CRC-23-0502en
dc.identifier.doi10.1158/2767-9764.CRC-23-0502
dc.identifier.iss7en
dc.identifier.issn2767-9764
dc.identifier.otherPubMedCentral: PMC11257085
dc.identifier.otherORCID: /0000-0002-8402-8670/work/164096064
dc.identifier.urihttps://hdl.handle.net/2164/23876
dc.identifier.vol4en
dc.language.isoeng
dc.relation.ispartofCancer research communicationsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectHumansen
dc.subjectRectal Neoplasms/pathologyen
dc.subjectNeoadjuvant Therapyen
dc.subjectMaleen
dc.subjectFemaleen
dc.subjectTranscriptomeen
dc.subjectMiddle Ageden
dc.subjectAgeden
dc.subjectCapecitabine/therapeutic useen
dc.subjectFluorouracil/therapeutic useen
dc.subjectGene Expression Profilingen
dc.subjectOxaliplatin/therapeutic useen
dc.subjectAntineoplastic Combined Chemotherapy Protocols/therapeutic useen
dc.subjectGene Expression Regulation, Neoplastic/drug effectsen
dc.subjectR Medicineen
dc.subjectUK Research and Innovation (UKRI)en
dc.subjectMR/M016587/1en
dc.subjectCancer Research UKen
dc.subjectCRUK/08/032en
dc.subjectSupplementary Dataen
dc.subjecthttps://aacrjournals.org/cancerrescommun/en
dc.subject.lccRen
dc.titleStratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signaturesen
dc.typeJournal articleen

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