Recombinant interleukin-1β dilates steelhead trout coronary microvessels : effect of temperature and role of the endothelium, nitric oxide and prostaglandins
| dc.contributor.author | Costa, Isabel A S F | |
| dc.contributor.author | Hein, Travis W | |
| dc.contributor.author | Secombes, Christopher J | |
| dc.contributor.author | Gamperl, A Kurt | |
| dc.contributor.institution | University of Aberdeen.Environment and Food Security | en |
| dc.contributor.institution | University of Aberdeen.Marine Alliance for Science and Technology for Scotland (MASTS) | en |
| dc.contributor.institution | University of Aberdeen.Biological Sciences | en |
| dc.contributor.institution | University of Aberdeen.Scottish Fish Immunology Research Centre | en |
| dc.date.accessioned | 2016-06-30T23:42:15Z | |
| dc.date.available | 2016-06-30T23:42:15Z | |
| dc.date.embargoedUntil | 2016-07-01 | |
| dc.date.issued | 2015-07 | |
| dc.description | © 2015. Published by The Company of Biologists Ltd. Acknowledgements We thank Wenjuan Xu and Xin Xu (Hein Lab) for their excellent instruction in microvessel techniques, Dr David Heeley (Biochemistry Department, MUN) for assistance with selecting an appropriate (non-vasoactive) protein stabilizer, Dr Zou (SFIRC, Aberdeen) for advice with regards to the use of rIL-1β and Gordon Nash (Gamperl Lab) for his assistance with the rIL-1β purification protocol. Funding This research was supported by a Natural Sciences and Engineering Research Council of Canada Discovery Grant [RGPIN249926] and Accelerator Supplement [RGPAS412325-2011] to A.K.G. a National Institutes of Health Grant [EY018420] to T.W.H., and a doctoral fellowship from Fundaçã o para a Ciência e a Tecnologia, Portugal [SFRH/BD/27497/2006] to I.A.S.F.C. Deposited in PMC for release after 12 months. | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 10 | |
| dc.format.extent | 606502 | |
| dc.identifier | 58010522 | |
| dc.identifier | e1309486-f7b0-4fe4-81ef-cc60b744ff34 | |
| dc.identifier | 26026045 | |
| dc.identifier | 84955461610 | |
| dc.identifier.citation | Costa, I A S F, Hein, T W, Secombes, C J & Gamperl, A K 2015, 'Recombinant interleukin-1β dilates steelhead trout coronary microvessels : effect of temperature and role of the endothelium, nitric oxide and prostaglandins', Journal of Experimental Biology, vol. 218, no. 14, pp. 2269-2278. https://doi.org/10.1242/jeb.119255 | en |
| dc.identifier.doi | 10.1242/jeb.119255 | |
| dc.identifier.iss | 14 | en |
| dc.identifier.issn | 0022-0949 | |
| dc.identifier.uri | http://hdl.handle.net/2164/6195 | |
| dc.identifier.vol | 218 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | Journal of Experimental Biology | en |
| dc.subject | Vasomotor responses | en |
| dc.subject | Oncorhynchus mykiss | en |
| dc.subject | Heart | en |
| dc.subject | Cytokine | en |
| dc.subject | Tone | en |
| dc.subject | Vascular resistance | en |
| dc.subject | QH301 Biology | en |
| dc.subject.lcc | QH301 | en |
| dc.title | Recombinant interleukin-1β dilates steelhead trout coronary microvessels : effect of temperature and role of the endothelium, nitric oxide and prostaglandins | en |
| dc.type | Journal article | en |