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A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy : the TURRIFIC randomised trial

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dc.contributor.authorHague, William M.
dc.contributor.authorCallaway, Leonie
dc.contributor.authorChambers, Jennifer
dc.contributor.authorChappell, Lucy
dc.contributor.authorCoat, Suzette
dc.contributor.authorde Haan-Jebbink, Jiska
dc.contributor.authorDekker, Marloes
dc.contributor.authorDixon, Peter
dc.contributor.authorDodd, Jodie
dc.contributor.authorFuller, Maria
dc.contributor.authorGordijn, Sanne
dc.contributor.authorGraham, Dorothy
dc.contributor.authorHeikinheimo, Oskari
dc.contributor.authorHennessy, Annemarie
dc.contributor.authorKaaja, Risto
dc.contributor.authorKhong, Teck Yee
dc.contributor.authorLampio, Laura
dc.contributor.authorLouise, Jennie
dc.contributor.authorMakris, Angela
dc.contributor.authorMarkus, Corey
dc.contributor.authorMarschall, Hanns-Ulrich
dc.contributor.authorMiddleton, Philippa
dc.contributor.authorMol, Ben W.
dc.contributor.authorMorris, Jonathan
dc.contributor.authorNewnham, John P.
dc.contributor.authorOvadia, Caroline
dc.contributor.authorPeek, Michael
dc.contributor.authorShand, Antonia
dc.contributor.authorStark, Michael
dc.contributor.authorThornton, Jim
dc.contributor.authorTimonen, Susanna
dc.contributor.authorWalker, Susan
dc.contributor.authorWarrilow, David
dc.contributor.authorWilliamson, Catherine
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Women’s Health Researchen
dc.date.accessioned2021-05-14T14:54:01Z
dc.date.available2021-05-14T14:54:01Z
dc.date.issued2021
dc.descriptionFunding The study sponsor and the funder (National Health and Medical Research Council (NHMRC) Medical Research Future Fund (MRFF) Lifting Clinical Trials and Registries Capacity (LCTRC) Grant Opportunity) have had no role in the study design; the collection, management, analysis, and interpretation of the data; the final writing of the report; and the decision to submit the report for publication.en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent854572
dc.identifier193233455
dc.identifierd6af0e06-b034-4cbe-87ac-ee3dbe89a168
dc.identifier33435904
dc.identifier85099226730
dc.identifier.citationHague, W M, Callaway, L, Chambers, J, Chappell, L, Coat, S, de Haan-Jebbink, J, Dekker, M, Dixon, P, Dodd, J, Fuller, M, Gordijn, S, Graham, D, Heikinheimo, O, Hennessy, A, Kaaja, R, Khong, T Y, Lampio, L, Louise, J, Makris, A, Markus, C, Marschall, H-U, Middleton, P, Mol, B W, Morris, J, Newnham, J P, Ovadia, C, Peek, M, Shand, A, Stark, M, Thornton, J, Timonen, S, Walker, S, Warrilow, D & Williamson, C 2021, 'A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy : the TURRIFIC randomised trial', BMC Pregnancy and Childbirth, vol. 21, no. 1, 51. https://doi.org/10.1186/s12884-020-03481-yen
dc.identifier.doi10.1186/s12884-020-03481-y
dc.identifier.iss1en
dc.identifier.issn1471-2393
dc.identifier.otherRIS: urn:8427CB7496C12F2E3F911F9C1A11CEA6
dc.identifier.otherRIS: Hague2021
dc.identifier.otherPubMedCentral: PMC7802989
dc.identifier.urihttps://hdl.handle.net/2164/16464
dc.identifier.vol21en
dc.language.isoeng
dc.relation.ispartofBMC Pregnancy and Childbirthen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectIntrahepatic cholestasis of pregnancyen
dc.subjectCholestatic pruritusen
dc.subjectBile acidsen
dc.subjectUrsodeoxycholic aciden
dc.subjectRifampicinen
dc.subjectMaternal and neonatal health outcomesen
dc.subjectR Medicineen
dc.subjectRG Gynecology and obstetricsen
dc.subjectSupplementary Informationen
dc.subject.lccRen
dc.subject.lccRGen
dc.titleA multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy : the TURRIFIC randomised trialen
dc.typeJournal articleen

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