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Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor

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dc.contributor.authorSteinmüller, S.A.M.
dc.contributor.authorThompson, K.
dc.contributor.authorAlenfelder, J.
dc.contributor.authorDrube, J.
dc.contributor.authorHoffmann, Carsten
dc.contributor.authorKostenis, E.
dc.contributor.authorThompson, D.
dc.contributor.authorHislop, J.N.
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2025-07-24T14:27:01Z
dc.date.available2025-07-24T14:27:01Z
dc.date.issued2025-11
dc.descriptionOpen Access via the Elsevier agreement We would like to thank M. Bouvier (University of Montreal, Canada) for providing the GEMTA constructs for BRET experiments, K. Pfleger (University of Western Australia) for providing luciferase tagged β-arrestin1 and 2, and GRK2 constructs, A. Inoue for generously supplying the ∆β-arrestin1/2 CRISPR/Cas9 edited cells, and A. Tobin for providing the M1 DREADD construct. We also thank B. Platt (University of Aberdeen) for technical guidance for calcium imaging.en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent8582362
dc.identifier305891716
dc.identifier7afa734f-34df-46ae-8908-6586f0b57321
dc.identifier40683329
dc.identifier105010941291
dc.identifier.citationSteinmüller, S A M, Thompson, K, Alenfelder, J, Drube, J, Hoffmann, C, Kostenis, E, Thompson, D & Hislop, J N 2025, 'Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor', Cellular Signalling, vol. 135, 112004. https://doi.org/10.1016/j.cellsig.2025.112004en
dc.identifier.doi10.1016/j.cellsig.2025.112004
dc.identifier.issn0898-6568
dc.identifier.otherRIS: urn:08A4C03EBE099045BA790D3EDF617D47
dc.identifier.otherORCID: /0000-0003-0948-9458/work/188340162
dc.identifier.urihttps://hdl.handle.net/2164/25753
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S089865682500419Xen
dc.identifier.vol135en
dc.language.isoeng
dc.relation.ispartofCellular Signallingen
dc.subjectR Medicine (General)en
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subject.lccR1en
dc.titleIdentification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptoren
dc.typeJournal articleen

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