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A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis

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dc.contributor.authorLeslie, Theresa K.
dc.contributor.authorTripp, Aurelien
dc.contributor.authorJames, Andrew D.
dc.contributor.authorFraser, Scott P.
dc.contributor.authorNelson, Michaela
dc.contributor.authorSajjaboontawee, Nattanan
dc.contributor.authorCapatina, Alina L.
dc.contributor.authorToss, Michael
dc.contributor.authorFadhil, Wakkas
dc.contributor.authorSalvage, Samantha C.
dc.contributor.authorGarcia, Mar Arias
dc.contributor.authorBeykou, Melina
dc.contributor.authorRakha, Emad
dc.contributor.authorSpeirs, Valerie
dc.contributor.authorBakal, Chris
dc.contributor.authorPoulogiannis, George
dc.contributor.authorDjamgoz, Mustafa B.A.
dc.contributor.authorJackson, Antony P.
dc.contributor.authorMatthews, Hugh R.
dc.contributor.authorHuang, Christopher L.H.
dc.contributor.authorHolding, Andrew N.
dc.contributor.authorChawla, Sangeeta
dc.contributor.authorBrackenbury, William J.
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cancer Centreen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2024-08-19T10:55:01Z
dc.date.available2024-08-19T10:55:01Z
dc.date.issued2024-08-16
dc.descriptionThe authors wish to acknowledge the roles of the Breast Cancer Now Tissue Bank in collecting and making available the samples and data, and the patients who have generously donated their tissues and shared their data to be used in the generation of this publication. The authors also thank Prof. Miles Whittington (Hull-York Medical School, UK), Dr. John Davey and Dr. Katherine Newling (Technology Facility, University of York, UK), and Prof. Lýdia Vargová (Charles University, Czechia) for providing invaluable advice. For the purpose of open access, a Creative Commons Attribution (CC BY) licence is applied to any author accepted manuscript version arising from this submission.en
dc.description.statusPeer revieweden
dc.format.extent17
dc.format.extent3844377
dc.identifier292165743
dc.identifier1c26d289-82ea-4061-ad95-989f4484219d
dc.identifier85199340801
dc.identifier39048659
dc.identifier.citationLeslie, T K, Tripp, A, James, A D, Fraser, S P, Nelson, M, Sajjaboontawee, N, Capatina, A L, Toss, M, Fadhil, W, Salvage, S C, Garcia, M A, Beykou, M, Rakha, E, Speirs, V, Bakal, C, Poulogiannis, G, Djamgoz, M B A, Jackson, A P, Matthews, H R, Huang, C L H, Holding, A N, Chawla, S & Brackenbury, W J 2024, 'A novel Na v 1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis', Oncogene, vol. 43, pp. 2578–2594. https://doi.org/10.1038/s41388-024-03098-xen
dc.identifier.doi10.1038/s41388-024-03098-x
dc.identifier.issn0950-9232
dc.identifier.otherORCID: /0000-0002-0602-4666/work/165791613
dc.identifier.urihttps://hdl.handle.net/2164/24052
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85199340801&partnerID=8YFLogxKen
dc.identifier.vol43en
dc.language.isoeng
dc.relation.ispartofOncogeneen
dc.subjectSubstantive connection via eligible employment contracten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectR Medicine (General)en
dc.subjectMolecular Biologyen
dc.subjectGeneticsen
dc.subjectCancer Researchen
dc.subjectSupplementary Informationen
dc.subjecthttps://doi.org/10.1038/s41388-024-03098-xen
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subject.lccR1en
dc.titleA novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasisen
dc.typeJournal articleen

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