University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury

Simple item page
dc.contributor.authorLecca, Daniela
dc.contributor.authorHsueh, Shih-Chang
dc.contributor.authorLuo, Weiming
dc.contributor.authorTweedie, David
dc.contributor.authorKim, Dong Seok
dc.contributor.authorBaig, Abdul Mannan
dc.contributor.authorVargesson, Neil
dc.contributor.authorKim, Yu Kyung
dc.contributor.authorHwang, Inho
dc.contributor.authorKim, Sun
dc.contributor.authorHoffer, Barry J.
dc.contributor.authorChiang, Yung-Hsiao
dc.contributor.authorGreig, Nigel H
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)en
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cell, Developmental and Cancer Biologyen
dc.date.accessioned2023-08-10T10:45:01Z
dc.date.available2023-08-10T10:45:01Z
dc.date.issued2023-03-06
dc.descriptionThe authors acknowledge support from their associated institutions which included (i) the Intramural Research Program, National Institute on Aging, NIH, USA, (ii) Aevis Bio Inc., S. Korea, (iii) Aevisbio Inc., USA; (iv) Aga Khan University, Pakistan; (v) University of Aberdeen, Scotland, UK; (vi) Case Western Reserve University School of Medicine, Cleveland, USA; (vii) Taipei Medical University, Taiwan. Funding This research was supported in part by: (i) The Intramural Research Program, National Institute on Aging, National Institutes of Health, USA, (AG000994), (ii) National Institutes of Health grant R56 AG057028, USA, (iii) the Technology Development Program of MSS (S2782046) and the National Research Foundation (NRF) grant funded by the Korean government (2021M3A9G2015889), and (iv) the Korea Research Institute of Bioscience and Biotechnology Research Initiative Program Grants, (v) the Sunny Brain Tumor and Brain Disease Research and Development Fund (106-5310-001-400), (vi) TMU-CWRU(CTSC) Pilot Program (107-3805-004-400), and (vii) the Ministry of Science and Technology, Taiwan (MOST 110-2314-B-038-106).en
dc.description.statusPeer revieweden
dc.format.extent21
dc.format.extent8550347
dc.identifier228059736
dc.identifier2544bee6-abac-4b5e-b999-66dbd45ec3a2
dc.identifier36872339
dc.identifier85149591926
dc.identifier.citationLecca, D, Hsueh, S-C, Luo, W, Tweedie, D, Kim, D S, Baig, A M, Vargesson, N, Kim, Y K, Hwang, I, Kim, S, Hoffer, B J, Chiang, Y-H & Greig, N H 2023, 'Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury', Journal of Biomedical Science, vol. 30, 16. https://doi.org/10.1186/s12929-023-00907-5en
dc.identifier.doi10.1186/s12929-023-00907-5
dc.identifier.issn1423-0127
dc.identifier.otherORCID: /0000-0001-8027-114X/work/145270780
dc.identifier.urihttps://hdl.handle.net/2164/21468
dc.identifier.vol30en
dc.language.isoeng
dc.relation.ispartofJournal of Biomedical Scienceen
dc.subjectNeuroinflammationen
dc.subjectThalidomideen
dc.subjectCereblonen
dc.subjectImmunomodulatory imide drugs 60 (IMiDs)en
dc.subjectNeurodegenerationen
dc.subjectMicrogliaen
dc.subjectTeratogenicityen
dc.subjectSpalt Like Transcription Factor (SALL4)en
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleNovel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injuryen
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Lecca_etal_JBS_Novel_Thalidomide_Like_VOR.pdf
Size:
8.15 MB
Format:
Adobe Portable Document Format
Download

Collections

All research

The Sir Duncan Rice Library

University of Aberdeen

Bedford Road

Aberdeen

AB24 3AA


Tel: +44 (0)1224 273330

Email: library@abdn.ac.uk

Share and keep up to date


FacebookTwitterWordpress