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Structural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysis

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dc.contributor.authorLutter, Liisa
dc.contributor.authorAl-Hilaly, Youssra K.
dc.contributor.authorSerpell, Christopher J.
dc.contributor.authorTuite, Mick F.
dc.contributor.authorWischik, Claude M.
dc.contributor.authorSerpell, Louise C.
dc.contributor.authorXue, Wei Feng
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2022-03-31T19:26:01Z
dc.date.available2022-03-31T19:26:01Z
dc.date.issued2022-04-15
dc.descriptionFunding Information: We thank Michel Goedert and Sjors Scheres for insightful discussions, and the members of the Xue group, the Kent Fungal Group and the Louise Serpell group for helpful comments throughout the preparation of this manuscript. This work was supported by funding from the Biotechnology and Biological Sciences Research Council (BBSRC), UK grant BB/S003312/1 (WFX and LCS), as well as Engineering and Physical Sciences Research Council (EPSRC), UK DTP grant EP/R513246/1 (LL). Research in the LCS lab, and YA-H is supported by funding from WisTa Laboratories Ltd (PAR1596).en
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent1587176
dc.identifier214987025
dc.identifierb14e171f-5612-4f8e-ac62-17267c65d00e
dc.identifier85124810391
dc.identifier35077765
dc.identifier.citationLutter, L, Al-Hilaly, Y K, Serpell, C J, Tuite, M F, Wischik, C M, Serpell, L C & Xue, W F 2022, 'Structural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysis', Journal of Molecular Biology, vol. 434, no. 7, 167466. https://doi.org/10.1016/j.jmb.2022.167466en
dc.identifier.doi10.1016/j.jmb.2022.167466
dc.identifier.iss7en
dc.identifier.issn0022-2836
dc.identifier.urihttps://hdl.handle.net/2164/18328
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85124810391&partnerID=8YFLogxKen
dc.identifier.vol434en
dc.language.isoeng
dc.relation.ispartofJournal of Molecular Biologyen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectamyloiden
dc.subjectatomic force microscopyen
dc.subjectcryo-electron microscopyen
dc.subjectpolymorphismen
dc.subjectstructural biologyen
dc.subjectR Medicine (General)en
dc.subjectBiophysicsen
dc.subjectStructural Biologyen
dc.subjectMolecular Biologyen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/S003312/1en
dc.subjectEngineering and Physical Sciences Research Council (EPSRC)en
dc.subjectEP/R513246/1en
dc.subjectSupplementary Informationen
dc.subject.lccR1en
dc.titleStructural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysisen
dc.typeJournal articleen

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