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Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

dc.contributor.authorMarcinkiewcz, Catherine A.
dc.contributor.authorMazzone, Christopher M.
dc.contributor.authorD'Agostino, Giuseppe
dc.contributor.authorHalladay, Lindsay R.
dc.contributor.authorHardaway, J. Andrew
dc.contributor.authorDiBerto, Jeffrey F.
dc.contributor.authorNavarro, Montserrat
dc.contributor.authorBurnham, Nathan
dc.contributor.authorCristiano, Claudia
dc.contributor.authorDorrier, Cayce E.
dc.contributor.authorTipton, Gregory J.
dc.contributor.authorRamakrishnan, Charu
dc.contributor.authorKozicz, Tamas
dc.contributor.authorDeisseroth, Karl
dc.contributor.authorThiele, Todd E.
dc.contributor.authorMcElligott, Zoe A.
dc.contributor.authorHolmes, Andrew
dc.contributor.authorHeisler, Lora K.
dc.contributor.authorKash, Thomas L.
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.date.accessioned2017-02-25T00:29:38Z
dc.date.available2017-02-25T00:29:38Z
dc.date.embargoedUntil2017-02-24
dc.date.issued2016-09-01
dc.descriptionWe acknowledge B. Roth for providing DREADD viral constructs and SertCre mice, and B. Lowell for providing CrfCre mice. We also thank A. Lopez, D. Perron, and A. Kendra for technical assistance with stereotaxic surgeries on mice, B. Geenen for technical assistance with immunohistochemistry and E. Dankoski for technical assistance with the FSCV. This work was supported by NIH grants AA019454, AA011605 (T.L.K.), the Wellcome Trust (098012) and the Biotechnology and Biological Sciences Research Council grant (BB/K001418/1) (L.K.H.) and by NIH grant K01AA023555 and the Alcohol Beverage Medical Research Fund (Z.A.M.). C.A.M. was supported by a postdoctoral NIAAA F32 fellowship (AA021319-02). C.M.M. is supported by a predoctoral NIAAA F31 fellowship (F31AA023440).en
dc.description.statusPeer revieweden
dc.format.extent5
dc.format.extent1833437
dc.identifier70274949
dc.identifier5e99f71e-cf52-4e26-be5f-749740f99818
dc.identifier27556938
dc.identifier84984653337
dc.identifier.citationMarcinkiewcz, C A, Mazzone, C M, D'Agostino, G, Halladay, L R, Hardaway, J A, DiBerto, J F, Navarro, M, Burnham, N, Cristiano, C, Dorrier, C E, Tipton, G J, Ramakrishnan, C, Kozicz, T, Deisseroth, K, Thiele, T E, McElligott, Z A, Holmes, A, Heisler, L K & Kash, T L 2016, 'Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala', Nature, vol. 537, pp. 97-101. https://doi.org/10.1038/nature19318en
dc.identifier.doi10.1038/nature19318
dc.identifier.issn0028-0836
dc.identifier.otherORCID: /0000-0002-7731-1419/work/30894621
dc.identifier.urihttp://hdl.handle.net/2164/8244
dc.identifier.vol537en
dc.language.isoeng
dc.relation.ispartofNatureen
dc.subjectlimbic systemen
dc.subjectneural circuitsen
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subject098012en
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/K001418/1en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleSerotonin engages an anxiety and fear-promoting circuit in the extended amygdalaen
dc.typeJournal articleen

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