Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model
| dc.contributor.author | Brice, Daniel P | |
| dc.contributor.author | Murray, Graeme I. | |
| dc.contributor.author | Wilson, Heather M. | |
| dc.contributor.author | Porter, Ross J. | |
| dc.contributor.author | Berry, Susan | |
| dc.contributor.author | Durum, Scott K. | |
| dc.contributor.author | McLean, Mairi H. | |
| dc.contributor.institution | University of Aberdeen.Applied Medicine | en |
| dc.contributor.institution | University of Aberdeen.Medical Sciences - Cardiovascular Group | en |
| dc.contributor.institution | University of Aberdeen.Institute of Medical Sciences | en |
| dc.date.accessioned | 2022-03-14T12:03:01Z | |
| dc.date.available | 2022-03-14T12:03:01Z | |
| dc.date.issued | 2022-03-11 | |
| dc.description | Funding: This research was funded by CICRA (CICRA: better lives for children with crohns and colitis. Available online: https://www.cicra.org (last accessed on 23 January 2022); Ph.D. studentship to DBP) and an NHS Grampian Endowment project grant. Acknowledgments: We wish to acknowledge the Grampian Tissue Biorepository for assistance in tissue preparation. Organoids were stored at −80 ◦C at the University of Aberdeen. Graphical abstract was created using Biorender with a licence for use in publication (agreement number AD22YOD1N6). DBP now at Lydia Becker Institute of Immunology and Inflammation and Wellcome Centre for Cell-Matrix Research, University of Manchester, UK | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 16 | |
| dc.format.extent | 1555813 | |
| dc.identifier | 214840970 | |
| dc.identifier | f8386a1a-e419-4e52-b6e2-1360da8a4b6f | |
| dc.identifier | 85126994453 | |
| dc.identifier.citation | Brice, D P, Murray, G I, Wilson, H M, Porter, R J, Berry, S, Durum, S K & McLean, M H 2022, 'Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model', Biology, vol. 11, no. 3, 427. https://doi.org/10.3390/biology11030427 | en |
| dc.identifier.doi | 10.3390/biology11030427 | |
| dc.identifier.iss | 3 | en |
| dc.identifier.issn | 2079-7737 | |
| dc.identifier.other | Bibtex: biology11030427 | |
| dc.identifier.other | ORCID: /0000-0002-1407-7274/work/109934275 | |
| dc.identifier.other | ORCID: /0000-0002-7443-2653/work/109934783 | |
| dc.identifier.uri | https://hdl.handle.net/2164/18213 | |
| dc.identifier.vol | 11 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | Biology | en |
| dc.subject | SDG 3 - Good Health and Well-being | en |
| dc.subject | IBD | en |
| dc.subject | colitis | en |
| dc.subject | cytokine | en |
| dc.subject | interleukin-27 | en |
| dc.subject | epithelium | en |
| dc.subject | organoid | en |
| dc.subject | gastrointestinal | en |
| dc.subject | permeability | en |
| dc.subject | R Medicine | en |
| dc.subject | Supplementary Data | en |
| dc.subject.lcc | R | en |
| dc.title | Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model | en |
| dc.type | Journal article | en |
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