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Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition : Analysis of a family-based cohort and twin study

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dc.contributor.authorvan Hecke, Oliver
dc.contributor.authorHocking, Lynne J
dc.contributor.authorTorrance, Nicola
dc.contributor.authorCampbell, Archie
dc.contributor.authorPadmanabhan, Sandosh
dc.contributor.authorPorteous, David J
dc.contributor.authorMcIntosh, Andrew M
dc.contributor.authorBurri, Andrea V
dc.contributor.authorTanaka, Haruka
dc.contributor.authorWilliams, Frances M K
dc.contributor.authorSmith, Blair H
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.date.accessioned2017-08-30T12:00:21Z
dc.date.available2017-08-30T12:00:21Z
dc.date.issued2017-02-22
dc.descriptionFunding: FMKW is supported by Arthritis Research UK grant 20682 and by EU FP7 project Pain-omics. AB reports an Ambizione personal career fellowship by the Swiss National Science Foundation and a project grant from the Swisslife Jubiläumsstiftung. Generation Scotland (www.generationscotland.org) has received core funding from the Chief Scientist Office of the Scottish Government Health Directorates CZD/16/6 and the Scottish Funding Council HR03006. The sponsor of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report, or the decision to submit for publication. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication. TwinsUK (www.twinsuk.ac.uk): the study was funded by the Wellcome Trust; European Community’s Seventh Framework Programme (FP7/2007-2013). The study also receives support from the National Institute for Health Research (NIHR)- funded BioResource, Clinical Research Facility and Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust in partnership with King's College London. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Acknowledgments We are grateful to the families who took part in GS:SFHS, the GPs and Scottish School of Primary Care for their help in recruiting them, and the whole Generation Scotland team, which includes academic researchers, clinic staff, laboratory technicians, clerical workers, statisticians and research managers. FMKW is supported by Arthritis Research UK grant 20682 and by EU FP7 project Painomics. AB reports an Ambizione personal career fellowship by the Swiss National Science Foundation and a project grant from the Swisslife Jubilaumsstiftung. https://figshare.com/articles/Chronic_pain_depression_and_cardiovascular_disease_linked_through_a_shared_genetic_predisposition_Analysis_of_a_family-based_cohort_and_twin_study/4681744en
dc.description.statusPeer revieweden
dc.format.extent19
dc.format.extent1461759
dc.identifier107333898
dc.identifierdeb960b3-577f-4c27-86ff-31dfd1d9e62e
dc.identifier28225781
dc.identifier85013471367
dc.identifier.citationvan Hecke, O, Hocking, L J, Torrance, N, Campbell, A, Padmanabhan, S, Porteous, D J, McIntosh, A M, Burri, A V, Tanaka, H, Williams, F M K & Smith, B H 2017, 'Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition : Analysis of a family-based cohort and twin study', PloS ONE, vol. 12, no. 2, e0170653, pp. 1-19. https://doi.org/10.1371/journal.pone.0170653en
dc.identifier.doi10.1371/journal.pone.0170653
dc.identifier.iss2en
dc.identifier.issn1932-6203
dc.identifier.otherPubMedCentral: PMC5321424
dc.identifier.urihttp://hdl.handle.net/2164/9231
dc.identifier.vol12en
dc.language.isoeng
dc.relation.ispartofPloS ONEen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectJournal Articleen
dc.subjectQH426 Geneticsen
dc.subjectArthritis Research UK (ARUK)en
dc.subject20682en
dc.subjectChief Scientist Office (CSO)en
dc.subjectCZD/16/6en
dc.subjectScottish Funding Councilen
dc.subjectHR03006en
dc.subjectWellcome Trusten
dc.subjectNational Institute for Health Research (NIHR)en
dc.subject.lccQH426en
dc.titleChronic pain, depression and cardiovascular disease linked through a shared genetic predisposition : Analysis of a family-based cohort and twin studyen
dc.typeJournal articleen

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